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Pharmacology for Canadian Health Care Practice 3rd Edition By Lilley ALL Chapters . CA$25.68   Add to cart

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Pharmacology for Canadian Health Care Practice 3rd Edition By Lilley ALL Chapters .

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Pharmacology for Canadian Health Care Practice 3rd Edition By Lilley ALL Chapters .

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  • August 24, 2024
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Test Bank For Pharmacology for Canadian Health Care
Practice 3rd Edition By Lilley ALL Chapters .
When is drug transfer to the fetus most likely to occur? - ANSWER: Last trimester

When is the fetus more susceptible to developing birth defects due to drugs or chemicals the mother
is exposed to? - ANSWER: First trimester

During the spectrum of life, when is there an increased risk of adverse affects to toxicity? - ANSWER:
At both ends of the spectrum; the very young and the very old

True or False: Breast fed infants are at risk for exposure to drugs consumed by the mother - ANSWER:
True

What is the general gastric pH for ages 1-12 - ANSWER: less acidic

in neonatal and pediatrics, how is their gastric emptying compared to adults? - ANSWER: slowed

in neonatal and pediatrics, how is their first-pass elimination compared to adults? - ANSWER: first-
pass elimination reduced

in neonatal and pediatrics, how is their IM absorption compared to adults? - ANSWER: Faster and
irregular

Fill the blanks: in neonatal and pediatrics, ___________________ bile salt formation
___________________ bioavailability. - ANSWER: reduced, decreases

Do neonates and pediatric patients have a higher or lower TBW? - ANSWER: Higher

What does total body water in neonates and pediatrics result in when given a water soluble drug? -
ANSWER: Increased distribution and dilution

in neonatal and pediatrics, what is the level of protein binding compared to an adult? - ANSWER:
Decreased

Immature blood-brain barrier means... - ANSWER: More drugs enter the brain

in the immature liver, what does it not produce enough of? - ANSWER: Microsomal enzymes
(cytochrome P450; P450 enzymes)

Older children may have increased metabolism, what would they require with drug administration but
not with infants? - ANSWER: Higher doses or more frequent administration

With an immature liver, what is an infant at risk of when given drugs? - ANSWER: Pediatric drug
toxicity

Fill the blanks: Kidney immaturity affects _________________ and ____________________. -
ANSWER: glomerular filtration rate, tubular secretion

Decreased perfusion rate of the kidneys may... - ANSWER: reduce excretion of drugs

Factors affecting pediatric drug dosage - ANSWER: -Skin is thin and permeable
-Stomach lacks acid to kill bacteria
-Lungs have weaker mucus barriers
-Body temperatures less well regulated, and dehydration occurs easily

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