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BCHM 270 Midterm Test Quizzes Solved 100% Correct |Verified Solutions
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Found at the exterior of a peptide embedded entirely in the cell membrane - Answer Nonpolar amino acids A, G, L, V, I, F, W, M, P + 1 charge - Answer Basic amino acids H, K, R - 1 charge - Answer Acidic amino acids D, E

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BCHM 270 Midterm Test Quizzes Solved 100%
Correct |Verified Solutions
Found at the exterior of a peptide embedded entirely in the cell membrane - Answer
Nonpolar amino acids
A, G, L, V, I, F, W, M, P


+ 1 charge - Answer Basic amino acids
H, K, R


- 1 charge - Answer Acidic amino acids
D, E


Intramolecular disulfide bond - Answer 2 C
(1 C can form disulfide bonds with other C groups)


Phosphorylated - Answer S, T, Y


Alpha helix breakers - Answer P
Bulky clusters: Y, W, L, V, F
Charged clusters: K, R, H, D, E


Ionizable side chains - Answer R, K, Y, C, H, E, D


Scurvy - Answer Caused by impaired hydroxylation of lysine and proline causing
unstable triple helices due to vitamin C deficiency.

, Prion disease - Answer Proteins are refolded from α-helix into β-sheet form, producing
long insoluble fibrils and a loss of function.


Alzheimer's disease - Answer Abnormal cleavage of the hydrophobic section of a
protein, which causes aggregation into long, insoluble neurotoxic fibrils.


Ostegenesis imperfecta - Answer Mutation of Gly-X-Y repeating sequences into bulky
amino acids, preventing assembly of helices into a mature collagen fiber (brittle bone
disease).


Respiratory acidosis - Answer Caused by a sharp increase of carbon dioxide in the blood.


Sickle cell anemia - Answer The aggregation of a mutated hemoglobin protein caused by
the substitution of glutamic acid to valine.


Ehlers-Danlos syndrome - Answer Proteins are refolded from α-helix into β-sheet form,
producing long insoluble fibrils and a loss of function.


Oxidoreductase - Answer Transfer electrons between molecules; catalyze oxidation-
reduction reactions.


Transferase - Answer Transfer functional groups between molecules.


Hydrolyase - Answer Cleaves molecules by the addition of water.


Lyase - Answer Adds atoms or functional groups to a double bond or removes them to
form double bonds.

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