Exam (elaborations)

Cannabis, Tobacco, and Vaping Final >> Pharm of Cannabis/Tobacco >> Health Class Tobacco and Vaping Real Exam Combined Set QUESTIONS AND CORRECT DETAILED ANSWERS {RATIONALES & IMAGES INCLUDED} |ALREADY GRADED A+| BRAND NEW VERSION

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Uploaded on September 22, 2024
Number of pages 116
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Type Exam (elaborations)
Contains Questions & answers

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Cannabis, Tobacco, and Vaping
Final >> Pharm of
Cannabis/Tobacco >> Health Class
Tobacco and Vaping
Real Exam Combined Set
QUESTIONS AND CORRECT
DETAILED ANSWERS
{RATIONALES & IMAGES
INCLUDED}
|ALREADY GRADED A+|
BRAND NEW VERSION!!

1) What system in activated from rewarding drugs?
- ANSWER dopamine system
2) How do endocannabinoids activate dopamine?
- ANSWER activates dopamine indirectly through inhibition of
glutamate and GABA
3) What CB1 antagonist can block opioid signaling?

,- ANSWER Rimonabant
4) Does cannabis activate opioid system?
- ANSWER yes
lessens withdrawal symptoms
cannabis safer than opioids
Problem Set 3: Appetite, Nausea, and Pain
5) Endocannabinoids most directly reduce the expression of which
hormone?
Neuropeptide Y
Leptin
Melanocortin
- ANSWER Leptin
- by decreasing leptin, you are inhibiting melanocortin but more directly
reducing leptin

6) Neuropeptide Y ________ appetite.
increases
decreases
- ANSWER increases
- it is increased by endocannabinoids, which is one of the ways it
increases appetite

, 7) The reward system received from eating is primarily dependent
on which endocannabinoid receptor?
CB1
CB2
TRPV1
GPR55
- ANSWER CB1
- increases ghrelin
- highly palatable foods induce reward response
-> CB1-depednet
- > reduce CB1 expression would cause negative feedback and
decreased response to endocannabinoids (fasting increases these
levels)
8) Rimonabant would be expected to ________ levels of
melanocortin.
increase
decrease
- ANSWER increase
- Rimonabant
-> produced as an anti-obesity drug
-> CB1 receptor antagonist
-> blocks the effects of endocannabinoids (CB1 agonist), which would
lead to icnrease levels of leptin and therefore melanocortin

, 9) Based on our current knowledge, which would work best as an
anti-emetic?
CB1 agonist
CB2 agonist
CB1 antagonist
CB2 antagonist
- ANSWER CB1 agonist
- THC - is equivalent to current serotonin blockers
-> anti-emetics - block acute, delayed, and anticipatory vomiting
-> low-dose THC required
-> a CB1 agonist
10) Administration of which dose would be most likely to
increase acute vomiting (ignore hyperemesis)?
1mg/kg THC
200mg/kg THC
1mg/kg CBD
200mg/kg CBD
- ANSWER 200mg/kg CBD
- high dose CBD increases vomiting
11) A physician aims to reduce nausea in a patient using CBDA.
Which route of administration of cannabis are they most likely to
prescribe?
smoking
vaporization

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Exam (elaborations)

Cannabis, Tobacco, and Vaping Final >> Pharm of Cannabis/Tobacco >> Health Class Tobacco and Vaping Real Exam Combined Set QUESTIONS AND CORRECT DETAILED ANSWERS {RATIONALES & IMAGES INCLUDED} |ALREADY GRADED A+| BRAND NEW VERSION

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