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Exam 1: NURS 615/ NURS615 (Latest 2024/ 2025 Update) Advanced Pharmacotherapeutics Complete Review |Qs & As| 100% Correct| Grade A (Verified Answers)- Maryville CA$15.23   Add to cart
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Exam 1: NURS 615/ NURS615 (Latest 2024/ 2025 Update) Advanced Pharmacotherapeutics Complete Review |Qs & As| 100% Correct| Grade A (Verified Answers)- Maryville
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Exam 1: NURS 615/ NURS615 (Latest 2024/ 2025 Update) Advanced Pharmacotherapeutics Complete Review |Qs & As| 100% Correct| Grade A (Verified Answers) Q: What factors affect the 1. Rate of absorption or how fast 2. Extent of absorption or how much of med reaches blood stream. Answer: 1. ...

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  • September 30, 2024
  • 18
  • 2024/2025
  • Exam (elaborations)
  • Questions & answers

Subjects

  • maryville adv pharmacotherapeutics exam
  • maryville adv pharmacotherapeutics exam 1
  • maryville adv pharmacotherapeutics exam 2
  • maryville adv pharmacotherapeutics exam 3
  • maryville adv pharmacotherapeutics

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  • NURS 615/ NURS615
  • NURS 615/ NURS615

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ExamI1:INURSI615/INURS615I(LatestI2024
/I2025IUpdate)IAdvancedI
PharmacotherapeuticsICompleteIReviewI|Qs
I&IAs|I100%ICorrect|IGradeIAI(VerifiedI
Answers)
Q:IWhatIfactorsIaffectItheI
1.IRateIofIabsorptionIorIhowIfast
2.IExtentIofIabsorptionIorIhowImuchIofImedIreachesIbloodIstream.


Answer:
1.IpHIofItheIenvironmentIwhereIabsorptionItakesIplace.
2.ISurfaceIareaIavailableI(smallIintestine)
3.IBloodIsupplyItoIabsorptionIsiteI
4.IPresenceIofIfood,IorIotherImaterialsIinIGII(IcanIpromoteIorIinhibitIabsorption)




Q:ITypesIofImedications

Answer:
WeakIacids:IwaterIsoluble,Ipolar,IandIchargedI(hardItimeIpassingIthroughIcellImembrane)
WeakIbases:IlipidIsoluble,Iunpolar,InonIchargedI(muchIeasierIpassIthrough).I
TheIsolubilityIandIdependabilityIofImedicationItoIpassIthroughIcellImembraneIallIdependsIonIt
heIRATIOIdeterminedIbyIenvironmentalIpHI&ISTRENGTHIofIweakIacidIorIbase.




Q:IHowIisItheIdrugIstrengthIorIaIweakIacidIorIweakIbaseImeasured?

Answer:
pKa

,Q:IWhatIisItheIpKa?

Answer:
pHIvalueIofIwhenIconcentrationsIofItheIunchargedIandIchargedIformsIequalIeachIother.I..




Q:IWhereIdoIweakIacidsItypicallyIabsorbIbest?

Answer:
ProximalIDuodenum

StomachIisIacidicIbutInotIsuitableIforIweakIacidsItoIabsorb..ImucousIlayer.




Q:IWhereIdoIweakIbasesItypicallyIabsorbIbest?

Answer:
DistalIileum




Q:IProcessIofIAbsorptionIforIPOImeds.

Answer:
Mouth,IabsorbedIthroughIwallsIofIsmallIintestine,ItransportedItoItheIliverI(via)IportalIvein.I
OnceIinIliverIhepaticIenzymesIwillIMETABOLIZEIdrug..I(knownIas..IfirstIpassImetabolismIor
IfirstIpassIeffect)..




Q:IWhatIisIfirstIpassImetabolism?

Answer:

, MetabolismIofIaIdrugIbeforeIitIentersIcirculation;IusuallyIthruIstomach,Iliver,Iintestine,Irectum
,Ilung.




Q:IFirstIpassImetabolismIofIPO.I...?

Answer:
BreakdownIofIMOSTImedsIintoItheIINACTIVEImetabolites.
ConvertsIprodrugsIintoIactiveImetabolites.I
BeforeIenteringIgeneralIcirculation.




Q:IRoutsIthatIbypassIfirstIpassIeffect?

Answer:
IV
StraightItoIsystemicIcirculationI100%IdrugIconcentrationIintoIcirculationIwithIIV.I

IMITransdermal,Isublingual,Iinhalation




Q:IBioavailabilityIorI"F"

Answer:
TheIfractionIofIanIorallyIadministeredI,educationIthatIreachesICIRCULATIONIinIUNCHANG
EDIFORM.I
IVI=IalwaysI100%




Q:IWhatIisItheIDistribution?

Answer:
TheImovementIofImedicationIfromIcirculationItoIbodyItissues.

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