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MICB 212 Midterm Exam All Possible Questions and Answers 2024/2025 Graded A+;University of British Columbia (UBC) CA$23.75   Add to cart
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MICB 212 Midterm Exam All Possible Questions and Answers 2024/2025 Graded A+;University of British Columbia (UBC)
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MICB 212 Midterm Exam All Possible Questions and Answers 2024/2025 Graded A+;University of British Columbia (UBC) MICB 212 Midterm Exam All Possible Questions and Answers 2024/2025 Graded A+;University of British Columbia (UBC)

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  • October 18, 2024
  • 38
  • 2024/2025
  • Exam (elaborations)
  • Questions & answers

Subjects

  • micb 212
  • what does mrsa stand for
  • micb 212 midterm exam all possible questions and a
  • what type of pathogen is listeria monocytogenes

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  • MICB 212
  • MICB 212

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MICB 212 Midterm Exam All Possible Questions and
Answers 2024/2025 Graded A+;University of British
Columbia (UBC)




[Course title]

,MICB 212 Midterm Exam All Possible Questions and
Answers 2024/2025 Graded A+;University of British
Columbia (UBC)

what does MRSA stand for Ans- methycillin-resistent staph aureus


what type of pathogen is MRSA Ans- extracellular bacteria


what type of pathogen is listeria monocytogenes Ans- intracellula bacteria


is staph aureus gram + or - Ans- positive


what kind of cells does S. aureus invade first Ans- skin epithelial cells
(keratinocytes)


what cytokines do keratinocytes secrete when breached? Ans- IL-1 alpha


what does IL-1 alpha bind and what happens after binding? Ans- IL-1R receptor
on keratinocytes, keratinocytes secrete chemokines CXCL1, CXCL2, CXCL8


what PAMPs are activating TLRs for S. aureus? Ans- lipoprotein and lipoteichoic
acid


which TLR is being activated for S. aureus? Ans- TLR2

,what does TLR2 binding in S. aureus result in? Ans- secretion of IL-1 beta by
innate immune cells (macrophages, DC, etc.)


how is S. aureus cleared at site of infection Ans- neutrophils phagocytose and
DIE. macrophages clear mess


what route does Listeria take to infect Ans- oral route


what type of cell does listeria infect initialy Ans- intestinal epithelial cels


how does listeria bypass physical barrier? Ans- adapted to survive low pH, can
escape phagosome, mucus


where does listeria end up after bypassing the barrier? Ans- spleen, liver, etc. via
the blood


what PAMPs are activating TLRs for listeria Ans- lipoprotein, lipoteichoic acid,
bacterial DNA and RNA (since it is intracellular)


which TLRs are being activated by listeria Ans- TLR 1, 2 ,6 (outside of cell), TLR9
(in endosome)


which innate cells are killing listeria Ans- macrophages


how do macrophages kill listeria Ans- phagosome fuses with lysosome to make
phagolysosome

, activation of ROS and NO kill bacteria


(in spleen and liver)


(cytotoxicity/Ab) is more effective for S. aureus Ans- Ab


what type of Ab best for S. aureus Ans- IgG


(cytotoxicity/Ab) is more effective for listeria Ans- cytotoxicity


what do virus infected epithelial cells release Ans- pro-inflammatory cytokines
and Type I interferon (IFN-alpha/beta)


how does IFN-alpha/beta act Ans- binds receptor on neighbouring cells to
increase antiviral gene expression


bind DCs to upregulate co-stimulatory proteins (B7)


which Ab is best for listeria Ans- IgG, IgA


which Abs are released for viral infection Ans- IgM, IgG, IgA


which TLRs activated by virus and by what PAMPs Ans- TL2 (envelop protein),
TLR3, 7 (viral RNA)

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