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CWS exam Practice Questions and Answers 100% Pass Cells make up the Epidermis? - ANSWER-Keratinocytes Keratinocytes are? - ANSWER-in stratum granulosum, relase lipids which continaun moisture, brick and mortar of skin Dermis contains? - ANSWER-cells for i

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CWS Exam Prep Questions and Answers 100% Pass Name the five types of Cell Adhesion Molecules? Which type enables cells to detect and interact with components of the extracellular matrix? - ANSWER-1. Cadherins 2. Immunoglobulin Superfamily (IGSF) 3. Selectins 4. Integrins 5. Mucins Integrins...

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cws exam practice questions and answers 100 pass

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CWS Exam Prep Questions and Answers

100% Pass

Name the five types of Cell Adhesion Molecules? Which type enables cells to detect and interact with

components of the extracellular matrix? - ANSWER✔✔-1. Cadherins

2. Immunoglobulin Superfamily (IGSF)

3. Selectins

4. Integrins

5. Mucins

Integrins allow cells to interact with the surrounding environment or components of the ECM.

What are the layers of the epidermis from most superficial to most deep? - ANSWER✔✔-Stratum

corneum

Stratum lucidum

Stratum granulosum

Stratum spinosum

Stratum basale (germinativa)

What are the layers of the dermis from most superficial to most deep? - ANSWER✔✔-Papillary dermis

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Reticular dermis

What is/are the primary cell type(s) of the stratum spinosum? - ANSWER✔✔-Langerhan's cells

What is/are the primary cell type(s) of the stratum basale? - ANSWER✔✔-Keratinocytes, Melanocytes,

Merkel cells

What is/are the primary cell type(s) of the stratum granulosum? - ANSWER✔✔-Corneocytes (terminally

differentiated keratinocytes)

What is/are the primary cell type(s) of the stratum corneum? - ANSWER✔✔-Dead keratinocytes

What is/are the primary cell type(s) of the dermis? - ANSWER✔✔-Fibroblasts, Mast cells, Macrophages,

Lymphocytes

Tissue loss includes only the epidermis. - ANSWER✔✔-Superficial

Tissue loss includes the epidermis and part of the dermis. - ANSWER✔✔-Partial thickness

Tissue loss includes the epidermis and all of the dermis. - ANSWER✔✔-Full thickness

Tissue loss includes subcutaneous tissues. - ANSWER✔✔-Subdermal

When does hemostasis or coagulation occur during the stages of healing? - ANSWER✔✔-Immediately

after tissue injury

When does inflammation occur during the stages of healing? - ANSWER✔✔-0-4 days

When does proliferation occur during the stages of healing? - ANSWER✔✔-4-21 days

How long can remodeling last? - ANSWER✔✔-Up to 2 years

What are the key cells of hemostasis? - ANSWER✔✔-Platelets

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What are the key cells of inflammation? - ANSWER✔✔-Neutrophils, Macrophages

What are the key cells of proliferation? - ANSWER✔✔-Fibroblasts, Epithelial cells, Endothelial cells,

Macrophages

What are the key cells of remodeling? - ANSWER✔✔-Fibroblasts

What produces PDGF? - ANSWER✔✔-Platelets and macrophages

What stimulates fibroblasts? - ANSWER✔✔-Platelet Derived Growth Factor

What is an integrin? - ANSWER✔✔-A cell surface receptor that enables cells to interact with components

of the ECM

What secretes MMPs and TIMPs? - ANSWER✔✔-Keratinocytes and fibroblasts

What regulates the activity of MMPs? - ANSWER✔✔-TIMPs

Fibroblasts play a key role in the extracellular matrix deposition of which types of proteins? -

ANSWER✔✔-Collagen

Elastin

Reticulin

Proteoglycans

Glycosaminoglycans

Myofibroblasts secrete which type of collagen? - ANSWER✔✔-Type I

Which type of collagen is primarily found in uninjured tissue? - ANSWER✔✔-Type I

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Which type of collagen is primarily found in wounds in the proliferative phase of wound healing? -

ANSWER✔✔-Type III

What is the transitional marker between the inflammatory and proliferative phases of healing? -

ANSWER✔✔-Macrophage migration into the wound site

Which cells are the last to arrive during the proliferative phase? - ANSWER✔✔-T lymphocytes

What are the three types of T lymphocytes and what are their functions? - ANSWER✔✔-1. Cytotoxic T

cells = directly target and kill any antigen-bearing cells

2. Helper T cells = activate macrophages and B lymphocytes

3. Suppressor T cells = down regulate inflammation and proliferation as the wound reaches maturity

What is considered the "first line of defense" in wound healing? - ANSWER✔✔-Neutrophils (PMN

leukocytes)

Mast cells are characterized by extensive cytoplasm with large granules which contain: - ANSWER✔✔-1.

Histamine

2. Heparin

3. Eicosanoids

4. Serotonin

5. Chondroitin sulfate

6. Vasoactive proteins

What type of collagen is primarily found in skin, tendon, vascular ligature, organs and bone (most

common in wounds)? - ANSWER✔✔-Type I

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Exam (elaborations)

CWS exam Practice Questions and Answers 100% Pass Cells make up the Epidermis? - ANSWER-Keratinocytes Keratinocytes are? - ANSWER-in stratum granulosum, relase lipids which continaun moisture, brick and mortar of skin Dermis contains? - ANSWER-cells for i

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