NR 565 / NR565 Advanced Pharmacology Midterm Exam Review| Chamberlain College
1. Typical Antipsychotics
- A class of older drugs to treat schizophrenia and related psychotic disorders primarily by reducing excess levels of dopamine in the brain
- do not give to elderly, neuroleptic mali...
- The most common group of antianxiety drugs, increases GABA and
decreases neuronal excitation
- do not mix with cns depressive agents
- Valium, xanax, ativan
5. Serotonergic anxiolytics
- Enhances serotonin to relieve anxiety
- No CNS depression, no anticonvulsant properties, very mild SE
- Buspirone, ipsapirone, gepirone
6. Barbiturates
- drugs that depress the activity of the central nervous system, reducing
anxiety but impairing memory and judgment, treat epilepsy, seizures,
insomnia
- do not suddenly discontinue, CNS depression does occur, decreases many
other medications such as beta blockers
- pentobarbital, -barbital etc
7. sedative-hypnotics
- Drugs that can act in the body either as sedatives or as hypnotics, depress the
CNS
, 8. Benzodiazepine hypnotics
- Diazepam, Midazolam, Zolazepam
- Potentiates the inhibitory action of GABA. Activation of the receptor causes
an influx of Cl- ion movement into the neuron and hyperpolarization and
inhibition of membrane depolarization
- Addicting
9. Nonbenzodiazepine hypnotics
- Zolpidem, Zaleplon, exZopiclone. "ALL ZZZs put you to sleep."
- MOA: act via BZ1 subtype of GABA receptor. Effects reversed by
flumazemnil
- Use: insomnia
- SE: ataxia, headaches, confusion. Short duration. Decreased depdence risnk
like bneozs and only modest daf-after pscyhomoter depression
10. mood stabilizers
- drugs used to control mood swings in patients with bipolar mood disorders
11. Lithium
- Inhibits IP3 second messenger cascade, mood stabilizer for bipolar
- therapeutic range 0.6 to 1.5
- causes congenital malformations
The benefits of buying summaries with Stuvia:
Guaranteed quality through customer reviews
Stuvia customers have reviewed more than 700,000 summaries. This how you know that you are buying the best documents.
Quick and easy check-out
You can quickly pay through credit card for the summaries. There is no membership needed.
Focus on what matters
Your fellow students write the study notes themselves, which is why the documents are always reliable and up-to-date. This ensures you quickly get to the core!
Frequently asked questions
What do I get when I buy this document?
You get a PDF, available immediately after your purchase. The purchased document is accessible anytime, anywhere and indefinitely through your profile.
Satisfaction guarantee: how does it work?
Our satisfaction guarantee ensures that you always find a study document that suits you well. You fill out a form, and our customer service team takes care of the rest.
Who am I buying these notes from?
Stuvia is a marketplace, so you are not buying this document from us, but from seller nurse_steph. Stuvia facilitates payment to the seller.
Will I be stuck with a subscription?
No, you only buy these notes for £10.23. You're not tied to anything after your purchase.
