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NURS305 Antimicrobial Drugs lecture 1 /LIBERTY UNIVERSITY £8.47   Add to cart

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NURS305 Antimicrobial Drugs lecture 1 /LIBERTY UNIVERSITY

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NURS305 Antimicrobial Drugs lecture 1 /LIBERTY UNIVERSITY

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  • June 14, 2022
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  • 2021/2022
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Antimicrobial Drugs
Lecture 1

,Antimicrobial Drugs

• Definition:
Used to prevent or treat infection

• Selective toxicity: The ability of a drug to
injure a targeted cell or target organism
without injuring other cells or organisms.
– Achieved by three mechanisms
• Disruption of bacterial cell wall
• Inhibits an enzyme unique to bacteria
• Disrupts bacterial protein synthesis

,Defense Against
Infection
– Normally humans live in harmony with
microorganisms around us. They live
within our bodies, skin, resp tract and
colon. We defend against infection
through these 5 things:
• Intact Skin
• Intact Mucous Membranes
• Anti-infective secretions
• Phagocytic cells
• Immune and inflammatory processes
– Many factors impair this process of
host defense

, Mechanisms of Action

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