Providing an in-depth, complete, and well-written description of IB biology of Option A1, including all the mechanisms to thoroughly understand neural development. It includes diagrams and annotated pictures, and all important keywords are highlighted.
Nuchal
development
Neurulation
The
development of a
fully -
formed
organism from a fertilised
egg is called
embryogenesis .
All endoderm) formed
germ layers ( ectoderm ,
tissues are derived from three initial mesoderm
,
cells to
via
gastrulation during embryonic development the
embryo from blastula
single layer of
→
.
process that
changes a with a
containing multiple layers of cells .
In chordates flexible notochord will develop during formation
,
a
gastrulation and lead to the
subsequent
of a neural tube .
The formation of a neural tube in
embryonic chordates occurs via the process of neurulation .
1 Notochord forms from mesoderm cells after complete
.
soon
gastrulation is .
2.
Signals from notochord cause inward
folding of ectoderm at the neural plate .
3. Ends of neural plate fuse and disconnect to form an autonomous neural tube .
I 2 3
1
Neurulation in a Xenopus Embryo Functions
, Spina Bifida
Closure of a neutral tube does not occur
simultaneously along the entire
length of the
embryo .
↳ The area where the brain forms is well advanced over the caudal 1 tail )
region, where closure occurs more
slowly .
Spina bifida is a birth defect
resulting in the incomplete closure of the neural tube ( it is associated with the vertebrae )
It is found in the lumbar and sacral where closure is
areas →
regions slowest .
The vertebral
processes do not fuse, leaving the spinal cord nerves exposed and prone to damage .
Trust forward or
laterally
Spina bifida Occult a
.
>
splits in the vertebrae are small
,
does not able the spinal cord does not protrude .
Spina bifida
Cystic a >
meningeal cyst forms which may include the spinal elements .
↳ Extreme cases →
paralysis or bladder dysfunction .
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