Lecture notes
Irritable bowel syndrome - GI system
- Module
- Systems of the Body 2
- Institution
- University Of Bristol (UOB)
A summary of Irritable bowel syndrome.
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Irritable bowel syndromeNo structural or biochemical marker for IBS, symptom based diagnosis.
Any of the following symptoms in the past six months plus:
Abdominal pain or discomfort
Bloating
Change in bowel habit
Plus at least two of:
Symptoms made worse by eating
Passage of mucous
Abdominal bloating
Altered passage of faeces e.g. straining, urgency etc.
Further investigation for red flag:
Unexplained weight loss
Rectal bleeding
FH of ovarian or bowel cancer
Loser stools for > 6 weeks in > 60
Pathophysiology:
Genetics and environment
Abnormal gastrointestinal motility
Visceral hypersensitivity and the brain gut axis
Psychological dysfunction
Microscopic inflammation
Gas displacement in healthy patients is not passive its actively propelled
independent of liquids and solids. IBS patients have impaired gas handling.
Gas pooling may cause pain.
Treatment is dietary and lifestyle changes including: Reduce insoluble fibre,
caffeine, chewing gum, Low Fermentable oligo / di and monosaccharides
(FODMAP) diet.
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