Summary Local anaesthetics pharmacology drug chart including mechanims of action indications and side effects
4 views 1 purchase
Module
Pharmacology
Institution
University Of The Witwatersrand (wits)
Book
Basic and Clinical Pharmacology 15e
Looking for a comprehensive, easy-to-understand study guide for local anaesthetics? Look no further than these detailed study notes, now available for sale!
These study notes are perfect for medical, nursing, and pharmacy students, as well as health professionals looking to brush up on their kno...
TEST BANK For Basic and Clinical Pharmacology, 15th Edition
TEST BANK For Basic and Clinical Pharmacology, 15th Edition
TEST BANK For Basic and Clinical Pharmacology, 15th Edition by Bertram G. Katzung, Verified Chapters 1 - 66, Fully Covered Complete Newest Version
All for this textbook (47)
Written for
University of the Witwatersrand (wits)
Pharmacology
All documents for this subject (8)
Seller
Follow
ilaraslabbert
Content preview
Local Anaesthetics
DRUGS MOA PK INDICATIONS SIDE EFFECTS ADMINISTRATION
Local infiltration, regional block, spinal &
Long-acting epidural anaesthesia Infiltration, Nerve
Bupivacaine
Slow onset of action: 30 mi surgical anaesthesia block, Spinal
several days of Analgesia
Local/topical
Infiltration Topical,
Onset of action: rapid
Lignocaine Intravenous regional anaesthesia (biers Infiltration, Nerve
Duration: intermediate
block) block, Spinal, IV
Epidural anaesthesia
Epidural anaesthesia
Amides
Local nerve block Psychogenic Infiltration, Nerve
Ropivacaine long acting
Infiltration Syncope block, Spinal
Analgesia Hyperventilation
Nausea vomiting
Mepivacaine intermediate acting dental practice, infiltration and nerve blocks
BP alterations
contains ester side chain which is Toxicity Infiltration, nerve
block voltage-gated sodium channels & reduce
hydrolysed - plasma esterases dental practice periodontal, infiltration and CNS block
Articaine influx of sodium
High lipid solubility - thiophene ring nerve blocks CVS
ions
Rapid onset (1-6 min) Respiratory
preventing depolarization of the membrane
metabolism: In Liver hepatic Allergy
Prilocaine blocking conduction topical anaesthesia Topical
cytochromes PABA
of the action potential
Topical gel: dentistry injection sites: minimize Metabisulfite
sensation Methaemoglobinaemia
Lozenge: Surface anaesthetic -pain relief of Prilocaine, articaine,
Benzocaine Topical
sore throats benzocaine
Throat spray Parasthesia
throat gargle articaine
Topical cream: pain relief in haemorrhoids
metabolism: Plasma cholinesterase's to and minor skin burns
Esters
inactive compounds Eye drops: ophthalmology in tonometry,
Tetracaine Topical
foreign body removal, suture removal
Oral gel: pain relief of mucous membranes
of mouth, lips, gums
Eye drops: ophthalmology in tonometry,
Oxybuprocaine foreign body removal, suture removal Topical
Has additive bactericidal activity
The benefits of buying summaries with Stuvia:
Guaranteed quality through customer reviews
Stuvia customers have reviewed more than 700,000 summaries. This how you know that you are buying the best documents.
Quick and easy check-out
You can quickly pay through credit card for the summaries. There is no membership needed.
Focus on what matters
Your fellow students write the study notes themselves, which is why the documents are always reliable and up-to-date. This ensures you quickly get to the core!
Frequently asked questions
What do I get when I buy this document?
You get a PDF, available immediately after your purchase. The purchased document is accessible anytime, anywhere and indefinitely through your profile.
Satisfaction guarantee: how does it work?
Our satisfaction guarantee ensures that you always find a study document that suits you well. You fill out a form, and our customer service team takes care of the rest.
Who am I buying these notes from?
Stuvia is a marketplace, so you are not buying this document from us, but from seller ilaraslabbert. Stuvia facilitates payment to the seller.
Will I be stuck with a subscription?
No, you only buy these notes for £3.80. You're not tied to anything after your purchase.
