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NAPLEX_ DDI and IV preparation Questions with 100% Actual correct answers | verified | latest update | Graded A+ | Already Passed | Complete Solution £6.46   Add to cart

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NAPLEX_ DDI and IV preparation Questions with 100% Actual correct answers | verified | latest update | Graded A+ | Already Passed | Complete Solution

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NAPLEX_ DDI and IV preparation Questions with 100% Actual correct answers | verified | latest update | Graded A+ | Already Passed | Complete Solution

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  • June 19, 2024
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  • 2023/2024
  • Exam (elaborations)
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Hkane
NAPLEX: DDI and IV preparation.
Name the 7 Mayjor CYP enzyme inducers - ANS-1. Phenytoin, 2. Smoking. 3.
Phenobarbitol. 4. oxcarbazepine. 5. Rifampin 6. carbamazepine 7. St Johns Wort

D. Dolutegravir. Dolutegravir is NOT a protease inhibitor it is an integrase inhibitor.
Protease inhibitors end with -"navir" while integrase inhibitors end with "-gravir". All
protease inhibitors increase serum concentrations of CYP450 substrates - ANS-All of
the following are proteas inhibitors known to be major inhibitors of CYP enzymes
except.
A. Ritonavir
B. Atazanavir
C. Darunavir
D. Dolutegravir
E. tipranavir

What is the expected drug-drug interaction when Valproate is used with lamotrigine?
A. increase AUC of lamotrigine.
B. decrease AUC of lamotrigine.
C. decrease AUC of valproate.
D. Increased AUC of valproate. - ANS-A. increase AUC of lamotrigine. Lamotrigine
dose must be lowered.

Which of the following antibiotics should be separated from cations (mag, alum,
calcium) to avoid decrease drug absorption? (Select all that apply)
A. Beta-Lactams.
C. Fluoroquinolones
D. Macrolides.
E. Tetracyclines. - ANS-C and E. Floroquinolones and tetracyclines (doxycycline,
tetracycline, minocycline) must be separated from antacids, multivitamins and
phosphate binders. Give ABX 2 hours before or 6 hours after these drugs.

The LATTIN acronym refers to drugs that are not compatible with PVC I.V. bags. What
drugs are included as part of this acronym? - ANS-L is for Lorazepam. A is for
Amiodarone. T is for Tacrolimus. T is for Taxane (paclitaxel). I is for Insulin. N is for
Nitroglycerine.

Which of the following antibiotics should *only* be mixed with normal saline. (Never ever
mix with dextrose). Select all that apply.

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