Clinical Pharmacology- Exam 1
Absorption - correct answer-Movement of a drug from outside the body and into the
bloodstream
ACE Inhibitors are used for patients with the following conditions: - correct answer-HTN,
CHF, CAD, DM, Kidney disease, MI, Scleroderma, and Migraines.
ACE Inhibitors are usually paired with... - correct answer-Diuretics
ACE Inhibitors... - correct answer-Cause vasodialation and reduces the amount of fluid in the
blood and tissues, leading to a lower BP
Adverse effect - correct answer-Effect that is more severe and can cause serious
complications
Agonist - correct answer-Activates the receptor cite of a cell and naturally mimics natural
body processes
ALL CARDIAC MEDS NEED ____________ & ___________ prior to administration - correct
answer-Blood Pressure and an Apical Pulse
Alpha Blockers - correct answer-Reduce the effects of norepinephrine, which leads to
vasodialation and a lowered BP
amlodipine (Norvasc) Drug type - correct answer-Long term calcium channel blocker
amlodipine (Norvasc) Side effects - correct answer-Swelling of the legs, tiredness, stomach
pain, nausea, flushing, arrhythmia, palpitations, and tremors
An oral dose will be _________ than an IV dose because of a difference in bioavailibility -
correct answer-Higher--- An oral dose needs more because of the first pass effect
Angioedema - correct answer-Severe swelling (Usually the face and lips) More common with
ACE Inhibitors and strong antibiotics. May take a while to show, so patients don't always
suspect that its the medication
Angiotensin-Converting Enzyme Inhibitor (ACE Inhibitor) - correct answer-Treats CHF and
Hypertension
Antagonist - correct answer-Drug that blocks the receptor cite of a cell- prevents a naturally
occurring body hormone/substance from accessing the cell
ARBs (Angiotensin II Receptor Blockers) - correct answer-Usually for those who are
intolerant of ACE Inhibitors
, atenolol (Tenormin) - correct answer-A beta blocker- treats angina and HTN. It also
decreases the heart rate and the workload of the heart.
atenolol (Tenormin) side effects - correct answer-Respiratory issues (wheezing and difficulty
breathing), Low libido, Triedness, depression, low sodium
Average BUN levels for a child - correct answer-5-18 mg/dL
Average BUN levels for a man - correct answer-8-20 mg/dL
Average BUN levels for a woman - correct answer-6-20 mg/dL
Beta Blockers - correct answer-They decrease HR and the contractility of the heart.They
limit epinephrine and its effects on the body.
Bioavailability - correct answer-% of the drug that actually reaches the bloodstream
Black Box Warning - correct answer-This drug can cause life threatening effects
Calcium Channel Blockers - correct answer-Slow the movement of calcium into the heart
and vessel cells. This causes the vessels to relax so the heart and body can get O2 rich
blood
Can you take hydralazine during pregnancy? - correct answer-YES
Can you take methyldopa while pregnant? - correct answer-YES
Captopril (Capoten) - correct answer-ACE Inhibitor, used to treat kidney disease in patients
with type 1 diabetes and eye disease
Captopril (Captoen) side effects include... - correct answer-Fever, flu like symptoms, edema,
chest pain, difficulty breathing, stomach pain, rash and itching, and hypokalemia.
Captopril is given to... - correct answer-Diabetics as the first line of treatment
Carvedilol (Coreg) - correct answer-Used to treat HTN, CHF, and to mitigate the effects of a
MI.
Common side effects of ACE Inhibitors - correct answer-Dry cough, Hyperkalemia, Fatigue,
Dizziness, Headache, and *Loss of taste*
Considerations for the Fentanyl Patch - correct answer-If this patch needs to be changed
into an oral medication, YOU MUST WAIT 16 HOURS (the half life of this medication is 16
hours) Overdose can cause respiratory distress.
Contraindication - correct answer-Personal/health related reason for not giving or taking a
drug