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IMMB 302 Immunology Exam 1 Questions With Answers Graded A+

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IMMB 302 Immunology Exam 1 Questions With Answers Graded A+ immunis meaning Exempt, protected The Immune System Defends the body against what? -Non-self (bacteria, virus, fungi, protozoa, tissue grafts) -Mutated self (cancer, misfolded proteins) physiological barriers of the immun...

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  • June 30, 2024
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  • 2023/2024
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IMMB 302 Immunology Exam 1 Questions
With Answers Graded A+
immunis meaning
Exempt, protected



The Immune System Defends the body against what?
-Non-self (bacteria, virus, fungi, protozoa, tissue grafts)
-Mutated self (cancer, misfolded proteins)



physiological barriers of the immune system
-Skin, Mucous membranes



white blood cells (leukocytes)
-Part of innate immunity (phagocytes)
-initiate inflammation, engulf, destroy invaders



white blood cells (lymphocytes)
-B Cells
-T Cells



B Cells
produce antibodies, provide memory



T Cells
T Helper Cells- Regulate, orchestrate response
T Cytotoxic Cells- Killer cells, attack invaders



Where in the body does the immune response occur?
-Lymphatic vessels, nodes (FBI, CIA Hang out)
-Bloodstream
-Thymus (T cells mature and are checked here)
-spleen (controls the level of RBCs/WBCs in blood)
-Bone Marrow (B and T cells produced here)
-Liver (produces antimicrobial chemicals)
-Brain (activates the sympathetic nervous system to tell bone marrow to make WBCs when needed)



Where does the T Cell mature?
thymus

,Where does the B Cell mature?
bone marrow



What are the components of innate immunity?
-General barriers (Skin)
-Mucus clearance
-Cellular (activities of phagocytes/inflammation)



adaptive immunity
-Develops over time (1-2 weeks)
-Activation of antigen specific B and T Cells
-B Cell Antibody humoral and T cell mediated
-Immunologic memory



Where does adaptive immunity occur?
lymphatic system



What part of the innate immunity process triggers specific cellular response?
Phagocytosis and inflammation (develops about 2 weeks)



Leukocytes
-phagocytic cells (simple, dumb and hungry)
-Part of innate immunity



Lymphocytes
B cells and T cells
-Part of adaptive immunity
-Capable of memory



What are antibodies' soluble components contributing to Humoral Immunity in blood?
-Neutralize toxins ("antitoxin")
-Precipitate toxins ("precipitin")
-Clump Bacteria ("agglutinin")



What is the use of Immunoglobulin/antibodies?
-antiserum from immune individual can protect non-immune
-leads to passive immunity (does NOT provide immunological memory)

, What provides the ability to produce active immunity?
Natural infection or vaccination
-Long-lived memory
-Based in long lived cells like memory B cells
-Memory Cells (quickly producing antibodies)



4 main categories of pathogens
viruses, bacteria, fungi, protozoan



What characteristics does innate immunity recognize in a foreign invader?
-Substances not found in human host, but are instead common to pathogens
-Pathogen-Associated Molecular Patterns (PAMPs)



Cellular Proteins that recognize PAMPs can be:
-Pattern Recognition Receptors (PRRs)
-Surface bound or intracellular
-Inherited through conservatory
-Human leukocytes have 10 PRRs
-Can be early profiled



The quick recognition system is followed by:
-Phagocytosis by leukocytes
-inflammation



Characteristics of inflammation
-Influx of blood/chemicals (compliment system)
-More leukocytes
-Quick elimination prevents infection



How does adaptive immunity recognize different pathogens?
-Can recognize subtle molecular differences
-Potential to recognize an infinite number of molecules through maturation



When a pathogen is recognized, what happens?
-Results in production of antibodies specifically tailored to the pathogen in question
-Neutralizes molecule



Are lymphocytes randomly generated?
-Yes, each lymphocyte has a unique antigen receptor with random gene arrangements

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