Summary
summary notes on cytoskeleton
- Module
- Medical sciences
- Institution
- University Of Central Lancashire Preston (UClan)
it consists of summary notes surrounding cytoskeleton
[Show more]
Seller
Follow
Content preview
The cytoplasmic matrix contains a complex network of following things like microtubules,actin filaments and intermediate filaments. - non- membranous organelles.
- These structural proteins provide structural and mechanical support to the cell and the
shape of the cell, and these proteins are important for the cellular and cytoplasmic
movement of the cell.
-
Actin filaments (microfilaments): it around
the inner edge of the cell as it thickens the
cortex, they resit tension.
Microtubules: They are found inside the cell where
they are responsible for maintaining the shape of the
cell by resisting compressive forces.
Intermediate filaments: are found throughout
the cell as they hold organelles of the cells in
place.
Functions of the cytoskeleton include:
1. Allow cell movement: enabling blood cells to move along the blood vessels walls,
migration of fibroblasts during wound healing and the movement of cells during
embryonic development.
2. Support and provide strength to the cell
3. Phagocytosis – engulf of components.
4. Cytokinesis – form of cell division
5. Cell to cell and cell to extracellular matrix adherence
6. Changes shapes of cell.
Microtubules
, - Composed of tubulin dimers
- Each tubulin dimers consists of two tightly bound tubulin molecules which include α-
tubulin and β-tubulin.
- γ-tubulin- forms the first ring at the -end.
- Tubulin are arranged in protofilaments.
- 13 protofilaments go side by side to create a cylinder of microfilaments with a hollow
core.
- The diameter of the microtubule is 25nm
- Microtubules are structurally polarized
- + end- corresponds to the α-tubulin. – growth region – nucleus
- - end- corresponds to the β-tubulin. – shortening region – periphery
- Most individuals of microtubules undergo phases of slow growth, rapid
depolymerization as this is known as dynamic instability process as this process consists
of three steps including:
1. Polymerization phase: where the GTP tubulin subunit is added to the + end of the
microtubule and a GTP cap is assembled to allow further growth to happen as
this requires Mg2+.
2. Release of hydrolysed phosphate (Pi): The hydrolysed phosphate is released from
the tubulin bound GTP.
3. Depolymerization phase: This is where the GTP tubulin subunits are released
from the -end at a faster rate.
- Transition from polymerization to depolymerization is known as catastrophe.
The benefits of buying summaries with Stuvia:
Guaranteed quality through customer reviews
Stuvia customers have reviewed more than 700,000 summaries. This how you know that you are buying the best documents.
Quick and easy check-out
You can quickly pay through credit card for the summaries. There is no membership needed.
Focus on what matters
Your fellow students write the study notes themselves, which is why the documents are always reliable and up-to-date. This ensures you quickly get to the core!
Frequently asked questions
What do I get when I buy this document?
You get a PDF, available immediately after your purchase. The purchased document is accessible anytime, anywhere and indefinitely through your profile.
Satisfaction guarantee: how does it work?
Our satisfaction guarantee ensures that you always find a study document that suits you well. You fill out a form, and our customer service team takes care of the rest.
Who am I buying these notes from?
Stuvia is a marketplace, so you are not buying this document from us, but from seller emanzahra. Stuvia facilitates payment to the seller.
Will I be stuck with a subscription?
No, you only buy these notes for £7.16. You're not tied to anything after your purchase.
Can Stuvia be trusted?
4.6 stars on Google & Trustpilot (+1000 reviews)
72042 documents were sold in the last 30 days
Founded in 2010, the go-to place to buy revision notes and other study material for 14 years now