NURS 8024 (Neuropharmacology) EXAM
3 REVISION Questions and Answers A+
Graded and Verified.
What is unique about Fos phenytoin and what is the MOA:
Correct Answer -Prodrug; rapidly converted to phenytoin in the blood -
EXCELLENT choice for AED
Name Three Benzodiazepines for AED TX:
Correct Answer -Diazepam (Valium), Lorazepam (Ativan) and
Clonazepam (Kronospan)
What is the MOA for Benzos?
Correct Answer -Potentiates GABA Response - Suppresses spread of
seizure activity
ADE with Benzo - BIG ONE?
Correct Answer -Sedation, Addictive effect and CYP450 / Pregnancy D
Name a Barbiturate:
Correct Answer -Phenobarbital
When would an NP prescribe phenobarbital?
Correct Answer -When other AEDs have not worked or for NEONATAL
Szs
,Name the Carbamazepine with a BBW of SJS and Blood dyscrasias?
Correct Answer -Tegretol
Name the AED that causes SJS and Toxic Epidural Necrosis?
Correct Answer -Lamictal
Which AED is used for Migraines Prophylaxis and cause oral
contraceptives to be less effective?
Correct Answer -Topiramate
Sodium Valproate / Valporic Acid has what BBW?
Correct Answer -Liver Toxicity, Pancreatitis and Teratogenicity
The _________ with valporic acid is a major consideration with drug
selection.
Correct Answer -BBW
Which AED would an NP prescribe for neonatal seizures?
Correct Answer -Phenobarbital
What is the #1 reason for TX failure with AEDs?
Correct Answer -Non-adherence
__________ ____________ ___________ may be an alternate treatment
for seizure patients unsuccessful with other drug txs.
Correct Answer -Vagal Nerve Stimulation
, Three Pregnancy Tips for AEDs:
Correct Answer -1. Don't take them as many cause problems
2. Take Folic Acid to avoid birth defects
3. Consult with Neurology before Rx
What ADE does the NP know when prescribing AEDs to women of child
bearing age?
Correct Answer -Barbiturates and Phenytoin can cause coagulations
disorders
Withdraw of AEDs should be done __________________ .
Correct Answer -Gradually
A HA lasting more than 2 hours and made worse by physical activity is a
______________ .
Correct Answer -Migraine
What is the 1st line for Migraine Drug Tx (mild to moderate)?
Correct Answer -NSAIDS (Aspirin, Ibuprofen, naproxen, diclofenac)
What ingredient is added to NSAIDs so treat migraine HAs?
Correct Answer -Caffeine
1st Line for moderate to severe Migraine HA?
Correct Answer -Triptans like Sumatriptan
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