,Test Bank - Focus on Nursing Pharmacology (9th Edition by Karch)
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Chapter 01 - Introduction to Drugs iy iy iy iy iy
A nurse working in radiology administers iodine to a patient who is having a computed tomography (CT)
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scan. The nurse working on the oncology unit administers chemotherapy to patients who have
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cancer. At the Public Health Department, a nurse administers a measles-mumps-rubella (MMR)
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vaccine to a 14-month-old child as a routine immunization. Which branch of pharmacology best
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describes the actions of all three nurses?
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Pharmacoeconomics
Pharmacotherapeutics
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Pharmacodynamics
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Pharmacokinetics
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i y Ans: B
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Pharmacology is the study of the biologic effects of chemicals. Nurses are involved with clinical
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pharmacology or pharmacotherapeutics, which is a branch of pharmacology that deals with the uses of
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drugs to treat, prevent, and diagnose disease. The radiology nurse is administering a drug to help
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diagnose a disease. The oncology nurse is administering a drug to help treat a disease.
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Pharmacoeconomics includes any costs involved in drug therapy. Pharmacodynamics involves how a iy iy iy iy iy iy iy iy iy iy iy
drug affects the body and pharmacokinetics is how the body acts on the body.
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A physician has ordered intramuscular (IM) injections of morphine, a narcotic, every 4 hours as needed for
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pain in a motor vehicle accident victim. The nurse is aware this drug has a high abuse potential.
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Under what category would morphine be classified?
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Schedule I iy
iy Schedule II iy
iy Schedule
i y III
iy Schedule IV iy
iy Ans: B
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,Test Bank - Focus on Nursing Pharmacology (9th Edition by Karch)
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Narcotics with a high abuse potential are classified as Schedule II drugs because of severe dependence
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, Test Bank - Focus on Nursing Pharmacology (9th Edition by Karch)
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liability. Schedule I drugs have high abuse potential and no accepted medical use. Schedule III
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drugs have a lesser abuse potential than II and an accepted medical use. Schedule IV drugs have
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When involved in phase III drug evaluation studies, what responsibilities would the nurse have?
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iy Working with animals who are given experimental drugs
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Choosing appropriate patients to be involved in the drug study
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iy Monitoring and observing patients closely for adverse effects
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iy Conducting research to determine effectiveness of the drug Ans: C
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Feedback:
Phase III studies involve use of a drug in a vast clinical population in which patients are asked to
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record any symptoms they experience while taking the drugs. Nurses may be responsible for helping
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collect and analyze the information to be shared with the Food and Drug Administration (FDA) but
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would not conduct research independently because nurses do not prescribe medications. Use of
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animals in drug testing is done in the preclinical trials. Select patients who are involved in phase II
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studies to participate in studies where the participants have the disease the drug is intended to treat.
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These patients are monitored closely for drug action and adverse effects. Phase I studies involve
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healthy human volunteers who are usually paid for their participation. Nurses may observe for
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adverse effects and toxicity.
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What concept is considered when generic drugs are substituted for brand name drugs?
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iy Bioavailability
Critical concentration iy
iy Distribution
Half-life
i y Ans: A
Feedback:
Bioavailability is the portion of a dose of a drug that reaches the systemic circulation and is available
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to act on body cells. Binders used in a generic drug may not be the same as those used in the brand
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name drug. Therefore, the way the body breaks down and uses the drug may differ, which may
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eliminate a generic drug substitution. Critical concentration is the amount of a drug that is needed to
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cause a therapeutic effect and should not differ between generic and brand name medications.
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Distribution is the phase of pharmacokinetics, which involves the movement of a drug to the body’s
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tissues and is the
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