MRCPsych Paper B Old Age Psychiatry
(Mrcpsychmentor) – Questions & Accurate Answers
Eye condition most commonly associated with Charles Bonnet Sy Right Ans
- Macular Degeneration
Antidepressants most likely to precipitate delerium in elderly Right Ans -
Imipramine and other tertiary amine tricyclics (amitriptyline or doxepine)
GP referral elderly patient with memory loss for 2 years. Alzheimers
confirmed with MMSE 9/30. CT shows generalised atrophy. Treatment?
Right Ans - Memantine (MMSE 0-10 indicates severe and decision is made
clinically
Most common side effect Rivastigmine Right Ans - Nausea
Half life and most common side effect Donepezil Right Ans - 70 hours and
nausea
Interferon alpha can cause which psychiatric illness Right Ans - Depression
(21-58%)
According to NICE, in which patient group is HMPAOSPECT not considered
helpful in differentiating Alzheimer's, vascular and frontotemporal dementia
Right Ans - Down's syndrome - show SPECT abnormalities throughout life
resembling Alzheimer's therefore test not helpful
What is characterised by fluent and empty speech Right Ans - Semantic
dementia or fluent progressive dementia (memory for recent better preserved
than remote unlike Alzheimer's)
Risk factors for charles bonnet syndrome Right Ans - Advanced age,
peripheral visual impairment, isolation, sensory deprivation, early cognitive
impairment
Which benzodiazepine most likely to exacerbate cognitive impairment in
patients with dementia Right Ans - Diazepam and those with long half lives
, Which antihistamine most likely to precipitate delerium in elderly Right
Ans - Promethazine
Estimated total population prevalence of dementia in uk Right Ans - 1.3%
(approx 650,000 people!)
Investigation to differentiate Alzheimer's from dementia with Lewy Bodies
Right Ans - DATscan
Risk factor for paraphrenia (3) Right Ans - Female, hearing/visual
impairment and isolation
Middle ground between normality and dementia Right Ans - Mild cognitive
impairment
Which antipsychotic proven to increase risk of stroke in dementia Right
Ans - Olanzapine (despite this, both olanzapine and risperidone are indicated
for BPSD in dementia)
Strongest risk factor for Alzheimer's Right Ans - Age!
70 year old female with bipolar disorder on Carbamazepine for years presents
with mania. Most appropriate next step? Right Ans - Continue
Carbamazepine and add Quetiapine
Most useful in diagnosis of dementia Right Ans - Clinical interview
Antidementia Drug binding allosterically go the nicotinic acetylcholine
receptor Right Ans - Galantamine
Prevalence of Charles Bonnet Syndrome in those visually impaired Right
Ans - 12%
Medication causing side effects of anxiety in elderly Right Ans - Salbutamol
(and other stimulants)
Most helpful when assessing for mild cognitive impairment Right Ans -
CAMcog (part of CAMDEX)
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