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Test Bank for Fundamentals of Biochemistry Life at the Molecular Level 5th Edition by Donald Voet, Judith G. Voet, Charlotte W. Pratt£14.63
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Test Bank for Fundamentals
of Biochemistry Life at the
Molecular Level 5th Edition
by Donald Voet, Judith G.
Voet, Charlotte W. Pratt
1Which of the following is a characteristic of water that makes it essential for life?
○ a) Water has a high vapor pressure.
○ b) Water is a non-polar solvent.
○ c) Water has a high heat capacity.
○ d) Water has a low dielectric constant.
○ Answer: c) Water has a high heat capacity.
2. Which of the following types of bonds is most important for the stabilization of
protein secondary structures such as alpha helices and beta sheets?
○ a) Disulfide bonds
○ b) Hydrogen bonds
○ c) Ionic bonds
○ d) Covalent bonds
○ Answer: b) Hydrogen bonds.
3. In the Michaelis-Menten equation, which assumption is made regarding the
enzyme-substrate complex (ES)?
○ a) The concentration of ES is constant during the reaction.
○ b) ES is rapidly converted to enzyme and product.
○ c) The enzyme is saturated with substrate at all concentrations.
○ d) The enzyme binds only a single substrate.
○ Answer: a) The concentration of ES is constant during the reaction.
4. Which of the following amino acids has a side chain that can form hydrogen
bonds and is often found in enzyme active sites?
○ a) Alanine
○ b) Glycine
○ c) Serine
○ d) Valine
○ Answer: c) Serine.
,5. Which process is responsible for the synthesis of glucose from non-carbohydrate
precursors?
○ a) Glycolysis
○ b) Gluconeogenesis
○ c) Glycogenolysis
○ d) Pentose phosphate pathway
○ Answer: b) Gluconeogenesis.
6. The peptide bond is a type of covalent bond that links amino acids in proteins.
○ Answer: True.
7. In an alpha helix, hydrogen bonds occur between every fourth amino acid residue.
○ Answer: True.
8. Fatty acids are stored in the body as free fatty acids.
○ Answer: False. (Fatty acids are stored as triacylglycerols.)
9. ATP hydrolysis is an endergonic reaction.
○ Answer: False. (ATP hydrolysis is an exergonic reaction.)
10. Allosteric enzymes follow Michaelis-Menten kinetics.
● Answer: False. (Allosteric enzymes often show sigmoidal kinetics, not Michaelis-Menten
kinetics.)
11. Which of the following processes generates the most ATP per molecule of
glucose?
○ a) Glycolysis
○ b) Citric acid cycle
○ c) Oxidative phosphorylation
○ d) Fermentation
○ Answer: c) Oxidative phosphorylation
12. Which functional group is present in all amino acids?
○ a) Hydroxyl group
○ b) Carboxyl group
○ c) Sulfhydryl group
○ d) Phosphate group
○ Answer: b) Carboxyl group
13. What is the primary structural difference between ribose and deoxyribose?
○ a) Ribose lacks an oxygen atom on carbon 3.
○ b) Deoxyribose lacks an oxygen atom on carbon 2.
○ c) Ribose contains an extra methyl group.
○ d) Deoxyribose has a double bond between carbon 1 and carbon 2.
○ Answer: b) Deoxyribose lacks an oxygen atom on carbon 2.
14. Which of the following best describes the induced fit model of enzyme activity?
○ a) The enzyme and substrate fit perfectly from the start.
○ b) The enzyme changes its shape slightly upon substrate binding.
○ c) The substrate is broken down before binding to the enzyme.
○ d) Enzyme activity is not dependent on substrate concentration.
○ Answer: b) The enzyme changes its shape slightly upon substrate binding.
15. Which molecule acts as the final electron acceptor in the electron transport
chain?
○ a) NAD+
○ b) Oxygen
○ c) FAD
○ d) Water
○ Answer: b) Oxygen
16. In a DNA double helix, adenine always pairs with which base?
, ○ a) Cytosine
○ b) Thymine
○ c) Guanine
○ d) Uracil
○ Answer: b) Thymine
17. Which of the following amino acids is positively charged at physiological pH?
○ a) Glutamic acid
○ b) Lysine
○ c) Aspartic acid
○ d) Serine
○ Answer: b) Lysine
18. The primary structure of a protein refers to:
○ a) The three-dimensional folding of the protein.
○ b) The sequence of amino acids.
○ c) The arrangement of beta sheets and alpha helices.
○ d) The interaction between subunits in a protein complex.
○ Answer: b) The sequence of amino acids.
19. Which process occurs in the cytoplasm and results in the conversion of glucose
into pyruvate?
○ a) Krebs cycle
○ b) Glycolysis
○ c) Oxidative phosphorylation
○ d) Gluconeogenesis
○ Answer: b) Glycolysis
20. Which of the following is NOT a property of enzymes?
○ a) They lower the activation energy of reactions.
○ b) They are consumed during the reaction.
○ c) They are highly specific to their substrates.
○ d) They can be regulated by inhibitors and activators.
○ Answer: b) They are consumed during the reaction.
Metabolism and Enzyme Kinetics (21–40)
21. Which vitamin is necessary for the synthesis of NAD+ and NADP+?
○ a) Vitamin B1
○ b) Vitamin B2
○ c) Vitamin B3 (Niacin)
○ d) Vitamin B12
○ Answer: c) Vitamin B3 (Niacin)
22. Which coenzyme is directly involved in the transfer of acyl groups?
○ a) Coenzyme Q
○ b) FAD
○ c) NAD+
○ d) Coenzyme A (CoA)
○ Answer: d) Coenzyme A (CoA)
23. A Lineweaver-Burk plot is used to determine:
○ a) The rate of substrate binding.
○ b) The turnover number of an enzyme.
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