SBOM III Final Exam Exam Master Review - Genetics & Immunology Questions and Answers Fully Solved 100%
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Module
SBOM
Institution
SBOM
Which of the following best defines an antigen? - ️️A substance that binds to a
specific site on the Fab fragments of antibodies
Cells infected by viruses can also signal the presence of intracellular infection by
expressing on their surfaces viral proteins that can be recognized by antibodi...
SBOM III Final Exam Exam Master
Review - Genetics & Immunology
Which of the following best defines an antigen? - ✔️✔️A substance that binds to a
specific site on the Fab fragments of antibodies
Cells infected by viruses can also signal the presence of intracellular infection by
expressing on their surfaces viral proteins that can be recognized by antibodies. Cells
bound by such antibodies can then be killed by a specialized lymphoid cell called a: -
✔️✔️Natural killer cell
The expression of the immune response involves a certain amount of inflammation, cell
infiltration, lymph node swelling, and even tissue destruction. Sometimes they are very
severe. There are signs of an immune response in nearly all infections. Therefore, it is
to be expected that there will nearly always be some contribution of the immune
response to pathological changes. Sometimes this forms the major part of the disease.
For example, in tuberculosis, much of the lung tissue damage is caused by the release
of destructive enzymes by what? - ✔️✔️Macrophages
As they divide, T cells differentiate and acquire the capacity to produce what other
structure? - ✔️✔️Cytokines
Type I hypersensitivity reactions are mediated by which of the following? - ✔️✔️IgE on
basophils and mast cells
Which of the following CD antigens is typical for helper T lymphocytes? - ✔️✔️CD4
As a result of gene rearrangement, what does each B cell produce? - ✔️✔️An antibody
of a single specificity
Elevated body temperature during acute phase response is due to the long-range
effects of: - ✔️✔️IL-1
IL-6
TNF-α
Which of the following immunoglobulin isotypes can be found in mucus secretions? -
✔️✔️IgA
The CD8+ T cells recognize antigenic peptides presented by: - ✔️✔️MHC I
, What is the ability of an antibody to distinguish its immunogen from other antigens
called? - ✔️✔️Specificity
For which of the following immunoglobulin isotypes are Fc receptors present on the
mast cells? - ✔️✔️IgE
Antigenic peptides that are derived from processed extracellular toxins are presented to
T cells by - ✔️✔️MHC II
The CD4+ T cells recognize antigenic peptides presented by - ✔️✔️MHC II
The HLA-DP, HLA-DR, HLA-DQ, and HLA-DM proteins belong to - ✔️✔️MHC II
Which of the following immunoglobulin isotypes is the strongest activator of the
complement system? - ✔️✔️IgM
Coating a microorganism with molecules that allow its destruction by immune cells is
known as what? - ✔️✔️Opsonization
In phagocytosis, foreign materials are engulfed and digested by immune cells. Before
phagocytosis can take place there must be preliminary (nonspecific) attachment of the
object to the phagocytic cell surface, followed by firmer specific attachment. The firm
attachment and the ingestion of particles is facilitated by what serum substances? -
✔️✔️Opsonins
A 25-year-old woman presents with watery eyes and a runny nose. The symptoms get
worse after she has been outside, especially if she plays in the grass with her 2-year-
old. Allergy testing reveals that she is highly allergic to several grass pollens. Allergy
shots using grass pollens as the antigens might be helpful.
Considering the most likely diagnosis and treatment intervention, what mechanism will
reduce the patient's symptoms? - ✔️✔️Decreased production of allergy-specific IgE
Allergy to nickel is a well-known cause of contact dermatitis. Patches of dermatitis under
a watch or on earlobes suggest that a patient should be patch-tested with a battery of
commonly implicated agents, including nickel and chromate. Of what is nickel dermatitis
an example? - ✔️✔️Type IV hypersensitivity
The rash produced by poison ivy, is caused by a T cell response to a chemical in the
poison ivy leaf. As the chemical is delivered by contact with the skin, this is called
"contact dermatitis". An important test in determining which antigen is responsible for
contact dermatitis is - ✔️✔️Patch test
IgE is mostly found fixed in the tissues on mast cells that bear receptors for it, as well as
on circulating basophils and activated eosinophils. The ligation of cell-bound IgE by
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