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NUR 431 Exam 1 - Antifungals/Antivirals Questions and Answers
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NUR 431 Exam 1 - Antifungals/Antivirals Questions and Answers
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NUR 431 Exam 1 - Antifungals/AntiviralsQuestions and Answers
what are the 4 systemic fungal infections - Answer-1. Aspergillosis
2. Blastomycosis
3. Cryptococcus
4. Histoplasmosis
which 2 systemic fungal infections that are opportunistic - Answer-aspergillosis
cryptococcus
which 2 systemic fungal infections are non-opportunistic - Answer-blastmycosis
histoplasmosis
what shape is yeast and how does it multiply - Answer-circular; budding daughters
what shape is mold - Answer-long, hollow
when do fungi cause disease? - Answer-if they can grow at the temperature of the
infected body type
if they aren't kept in check by normal flora
immunocompromised
poor nutritional status
where is aspergillosis found - Answer--hospital construction & renovation in dust
-travels in airvents
-soil, water, decaying vegitation
when does aspergillosis cause infection - Answer-OPPORTUNISTIC
causes infection in immunocompromised patients (chemotherapy, transplant, HIV)
nursing consideration of aspergillosis - Answer-move immunocompromised patients
away from hospital construction; airborne
what is cryptococcus usually seen as - Answer-meningitis
cryptococcus is most serious in what patients - Answer-immunocompromised
where is cryotococcus found - Answer-bird droppings
in soil that's contaminated
, blastomycosis is an epidemic in which part of the US - Answer-Eastern US
blastomycosis causes what - Answer-chronic lesions on skin and lungs
is blastomycosis opportunistic or non-opportunistic - Answer-non-opportunistic
what does histoplasmosis effect - Answer-the lungs - inhale spores of the fungi that
causes an infection and can spread to the rest of the body
cause of histoplasmosis - Answer--bird & bat droppings
-contaminated soil
-chicken coups
-caves
symptoms of histoplasmosis - Answer-flu-like cough
chest pain
dyspnea
fever
weight loss
hemoptysis
is histoplasmosis opportunistic or non-opportunistic - Answer-non-opportunistic
what are the 3 polyene antifungals - Answer-amphotericin B
nystatin
micafungin
what are the azole antifungals - Answer-Fluconazole
Itraconazole
Voriconazole
Posaconazole
Isavuconazonium sulfate
amphotericin B indication - Answer-potentially fatal systemic fungal infections
amphotericin B MOA - Answer-binds to sterols in fungal cell membranes; causing
increased permeability leading to cell leakage and death
why is amphotericin B binding to sterols problem - Answer-human cells also contain
sterols so this attacks out own cells making us feel miserable
adverse effects of amphtericin B - Answer-NEPHROTOXICITY
Infusion reaction:
-hypotension
-fever
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