PACOP Bundled Exams with Complete Solution | Verified | Guaranteed Success

The driving force for passive absorption of a drug is the: a. specific carrier proteins and shows saturation kinetics b. concentration gradient across a membrane separating body compartment c. both d. none - b. concentration gradient across a membrane separating body compartment Physical factor...

1. Pharmacodynamics is: A. The science that examines the interrelationship of the physiochemical properties of the drug and the route of administration on the rate and extent of systemic drug absorption B. The science of the kinetics of drug absorption, distribution and elimination C. The part o...

1. Most of the official drugs containing calcium and zinc are assayed by: A) EDTA method B) Gravimetry C) Nonaqueous titrimetry D) Acidimetry - A 5. The following compounds are assayed by acidimetrically, except: A) Sodium hydroxide B) Caffeine C) Citric acid D) Zinc oxide - C 2. Type of a...

C - All are shrub/tree exudates EXCEPT a. Karaya B. Tragacanth C. Agar D. Acacia D - "Food of the gods" A. Coffee B. Tea C. Cassia D. Theobroma C - Alkaloid used as a skeletal muscle relaxant A. Papaverine B. Cocaine C. Tubocurarine D. Berberine B - 1,3,7- trimethyxanthine A. Theob...

The sudden unexpected occurrence of a disease in a given population: A) Outbreak B) Zoonotic C) Endemic D) Sporadic - A) Outbreak A causative agent of peptic ulcer: A) Escherichia coli B) Bordetella pertussi C) Shigella dysenteriae D) Helicobacter pylori - D) Helicobacter pylori The "four...

Rays which have no mass and no charge but of very high energy and excellent penetrating power are called? - Gamma Examples of antacids which cause rebound hyperacidity - NaHCO3 & CaCO3 Which anion evolves a gas with a fruity odor when treated with conc sulfuric acid and ethanol? - CH3COOWhic...

2. An example of a weakly basic prodrug that when protonated, form covalent disulfide linkages with H+/K+ ATPase and inactivates it: A. Maalox® B. Nexium® C. Tagamet® D. Buscopan® - B. Nexium® 3. Anti-ulcerant drugs exert their effect through which of the following mechanism/s: I. Stimu...

In LADMER system, L stands for liberation as the first step which determines the following aspects, except: a. onset of action c. rate of absorption b. type of preparation d. bioavailability - b. type of preparation The ultimate evaluation of dosage forms or delivery system is in: a. disintegra...

1. A means of administering drugs as formulated preparations is called: a. pharmaceutical b. drug delivery system c. dosage forms d. any of the above - D 2. A manufacturer who produces the products of a company without manufacturing facilities is a/ an: a. ethical manufacturer b. proprietary ...

1. Which of the following is(are) true regarding phase I drug metabolism? I. Also known as conjugation reaction II. Includes oxidation, reduction, hydrolysis III. Generally tends to provide a functional group or "handle" to the molecule a. I, II and III b. I and II only c. I only d. II and ...

A glucosan yield glucose units on hydrolysis. While inulin is a ____ a. fructosan b. hexosan c. pentosan d. diosan e. all of these - A The usual source of tannins from plants are from the : a. barks/stems b. seeds c. roots d. rhizomes e. all of these - A Ethanol and citric acid are produced by t...

1. A glucosan yield glucose units on hydrolysis. While inulin is a a. fructosan b. hexosan c. pentosan d. diosan e. all of these - A 2. The usual source of tannins from plants is the: a. bark/stems b. seeds c. roots d. rhizomes - A 3. Ethanol and citric acid are produced by the cellular r...

1. The functional group attached to the acyl amino group is called a/an: A) Phenoxyethyl B) Isoxazoyl C) Imidazole D) Benzyl E) Methoxypheny - B) Isoxazoyl 2. Halogen substituents are best placed in what position? A) 1,2-substitution B) 1,3-substitution C) 1,4-substitution D) BothAandB E)...

The inhibition in noncompetitive reaction _________________. a. competes with the active site of the enzyme b. binds simultaneously with substrate other than the active site c. increases the rate of reaction d. both b and c - B The order and sequence of amino acid in a polypeptide determines wh...