BMTCN Study questions and answers 2024

The cluster of differentiation system is used to: a. classify cell surface proteins on leukocytes. b. identify different types of cytokines. c. crossmatch for blood product transfusion. d. measure immune function. - ANSWER-The cluster of differentiation system classifies cell surface proteins. ...

BMTCN Study Myeloid - ANSWER-erythrocyte, platelets, neutrophil, basophil, eosinophil, monoblast, macrophage, monocyte lymphoid - ANSWER-pre- B cell, pre-t cell, plasma cell, natural killer cell, t lymphocyte innate immunity - ANSWER-occurs naturally- phagocytes release inflammatory mediators ...

BMTCN Exam hematopoietic stem cells - ANSWER-RBCs, WBCs, platelets Red marrow produces - ANSWER-hematopoietic stem cells Yellow marrow produces - ANSWER-stromal stem cells stromal stem cells produce - ANSWER-fat, cartilage and bone Hematopoietic stem cells develop - ANSWER-prior to birth, produ...

BMTCN Review Chapter 1-Basic Concepts and Indications for Transplantation Goal of Transplant - ANSWER--Cure disease -Increase disease free survival Hematopoiesis - ANSWER--Regulation, production and development of blood cells -Pluripotent Stem cells -Progenitor Stem Cells. -Myeloid and lymph...

TRANSPLANT PREP REGIMENS - ANSWER-Treatment leading up to transplant Acronyms: Ara-C BCNU BU Cy DLT SCT TBI - ANSWER-Cytarabine Carmustine Busulfan Cyclophosphamide Dose limiting toxicity DStem cell transplant Total body irradiation Induction chemotherapy - ANSWER-The first treatment...

BMTCN Ch 5 - GVHD overall incidence of GVHD? - ANSWER-20-80% mortality rates d/t GVH? matched sibling vs unrelated - ANSWER-18 % matched ib 20% unrelated What is GVH? - ANSWER-T cells from the donor recognize the recipient's cells as foreign and attack how does classic acute GVHD present - A...

Immunoglobulins are secreted by which type of cell? A. B-lymphocyte B. Megakaryocyte C. T-lymphocyte D. Natural killer - ANSWER-A. B-lymphocyte B lymphocytes synthesize and secrete immunoglobulins. Which portion of the immunoglobulin activates the complement pathway? A. MHC Class I B. Fab C...

BMT CERTIFICATION COURSE What does Red Bone marrow do - ANSWER-Produces Hematopoietic Stem cells that create RBC, plt, and WBC found in long and flat bones Think: Red like red blood cells What does Yellow Bone Marrow do? - ANSWER-Both Yellow marrow and fat cells produce stromal stem cells that ...

BMTCN Chapter 1: Basic Concepts and Indications for Transplantation Which of the following is an example of a myeloid cell? A. Thymus-derived cells (T cells) B. Bone marrow-derived cells (B cells) C. Monocytes D. Natural killer cells - ANSWER-C. Monocytes Several factors affect immune reconst...

BMTCN Chapter 1 Two types of marrow - ANSWER-red and yellow red marrow - ANSWER-thick, blood like material found in flat bones and the ends of long bones; location of blood cell formation yellow marrow - ANSWER-soft, fatty material found in the medullary cavity of long bones Hematopoietic loca...

BMTCN Chapter 5: Graft-versus-Host Disease T.R. is a 28-year-old woman with acute myeloid leukemia in her second complete remission who is admitted for a matched unrelated allogeneic stem cell transplantation. Her conditioning regimen is as follows: Myeloablation (busulfan/cyclophosphamide) and...

A patient developed type 4 PTLD three years after an allogeneic HSCT. Which of the following treatment interventions would the nurse expect an order for? - ANSWER-Aggressive chemotherapy Red bone marrow produces - ANSWER-hematopoietic stems cells that create red blood cells, white blood cells an...

The administration of Epstein-Barr virus (EBV) cytotoxic T-lymphocytes has been found to be a feasible therapeutic option in which EBV mediated-disease process? a) Lymphoproliferative disease b) Neuroblastoma c) Nasopharyngeal rhabdomyosarcoma d) Acute lymphocytic leukemia A) Lymphoproliferati...

What type of transplants commonly have PTLD as a secondary malignancy? - ANSWER-Allo HSCT with T-cell depleted graft Therapies associated with therapy-related acute leukemia and MDS - ANSWER-alkylating agents (eg. Cytoxan, cisplatin, melphalan, busulfan, ifos) , radiation, topoisomerase II inhib...