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Pharmacology - Chapter 45 - Calcium Channel Blockers Review Questions and Correct Answers

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MOA - Calcium Channel Blockers - Prevent Calcium ion from entering cells - Greatest impact is on heart, arterioles, and arteries Therapeutic uses - CCBs Hypertension, angina pectorals, cardiac dysrhythmias Explain the physiologic consequences of calcium channel blockers on vascular smooth muscle C...

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Pharm Study Guide (Calcium Channel Blockers) Ch 45 Questions and Correct Answers

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Calcium channel blockers (CCBs) lower BP by __________ Vasodilation CCBs differ from nitrates in that they do not cause vasodilation of ___________ Veins (venous system) Dihydropyridine CCBs primarily affect _________ Arterioles The three effects of the CCBs verapamil and diltiazem on the heart a...

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MK 3 - CCB, Chest tubes, CHD, Infectious Diseases Questions and Correct Answers

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Calcium Channel Blockers -CCBs are like "valium" for your heart --Valium calms you down. Therefore, CCB relaxes and slows down the heart ---If the heart is tachycardic, tachyarrhythmia, or heart attack → needs to be rested → GIVE CCB ---If you are in shock, or you are in heart block → needs to...

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Chapter 48 Calcium Channel Blockers Practice Questions and Correct Answers

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Calcium Channel Blockers Hypertension Angina Pectoris Cardiac dysrhythmias CCBs that target both vascular smooth muscle and the hearts NONdihyrdopyridines Verapamil Diltiazem CCB that targets vascular smooth muscle only DIHYDROPYRIDINES Nifedipine Calcium channel open Contractile process Calcium...

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Calcium Channel Blockers Test Questions and Correct Answers

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All CCB are racemic mixtures except? Dilt and Nifedipine Non-Dihydropyridines Verapamil and diltiazem Dihydropyridines Nifedipine, Nicardipine, Nimodipine, Felodipine, Isradipine, Nisoldipine Amlodipine, Clevidipine Adverse affects of CCBs are similar except that dihydropyridines never cause what...

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Calcium Channel Blockers Practice Test Questions and Correct Answers

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nondihydropyridine CCB include verapamil & diltiazem Verapamil is a NDH CCB Diltiazem is a NDH CCB Nondihydropyridine CCBs can be used to treat - HTN - stable angina - arrhythmias - atrial fibrillation NDH CCB deacrease HR & slow AV node conduction * may cause bradycardia & AV block * Counselin...

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Calcium Channel Blockers - Pharm Test 1 Questions and Correct Answers

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A diabetic patient suffers from effort angina, they have tried beta blockers before but are worried about experiencing a hypoglycemic incident while on the beta blocker. What would be the next best drug to treat this patient's angina? a. Verapamil b. Nifedipine c. Metoprolol d. Bumetanide ANS: A - v...

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CCBs and Beta-Blockers to Treat Angina Review Questions and Correct Answers

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Ca2+ Channel Blockers (CCBs) groups Dihydropyridine (DHP) groups NonDihydropyridine groups Dihydropyridine (DHP) groups *Amlodipine (Norvasc®) Felodipine Isradipine Nicardipine Nifedipine (Procardia®) Nimodipine Nisoldipine NonDihydropyridine groups *Verapamil (Calan®) Diltiazem (Cardizem®) ...

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Calcium Channel Blockers Practice Exam Questions and Correct Answers

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What are the three main classes of calcium channel blocking drugs? 1. Dihydropyridine 2. Benzothiazepines 3. Phenylalkylamines What drug is the benzothiazepine prototype? Diltiazem What drug is the phenylakylamine prototype? Verapamil What is the common suffix used by the dihydropyridine class? -...

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Calcium Channel Blockers Study Questions and Correct Answers

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What is the ion that is important for the depolarization of the nodal cell? Ca++ What are the potential effects of CCBs? 1) Reduce cardiac Automaticity 2) Reduce AV nodal conduction 3) Cause vasodilation What are the three main chemical classes of CCBs? 1) Phenylalkylamines 2) Benzothiazepines 3) ...

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Pharmacology I - Calcium Channel Blockers Questions and Answers

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Currently, all CCBs on the market target the __-type voltage activated calcium channel. A) T B) N C) R D) L E) P/QD) L *Currently, all CCBs on the market traget the L-type channel.* CCBs have greater effect on *arterial* or *venous smooth muscle.*CCBs have greater effect on *arterial sm...

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Calcium Channel Blockers Review Questions and Correct Answers

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calcium channel blockers Effect the heart, and blood vessels. CCBs are widely used to treat hypertension, angina pectoris and cardias dysrhythmias. calcium and the heart Calcium regulates contraction in vascular smooth muscle and cardiac muscle. In cardiac/vascular smooth muscle (VSM), the influx...

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Calcium Channel Blockers (CCBs) Practice Questions and Answers

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Calcium Channel Blockers (CCBs) CCBs work by decreasing calcium entry through calcium channels. By regulating the movement of calcium, contraction of vascular smooth muscle is controlled, which causes blood vessels to dilate. This reduces blood pressure and workload on the heart, so this type of med...

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510 CCB Study Guide- Questions and Correct Answers

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The primary cause of angina pectoris is an imbalance between --- --- of the heart and --- --- to the heartoxygen requirement; oxygen supply episodes of angina in unstable angina occur at --rest unstable angina is typically caused by -- -- around an atherosclerotic plaque causing a reduction in blo...

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3 – CCBs Practice Questions and Correct Answers

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Main effects of CCBs (3) Slow HR Decrease BP SM relaxation 3 classes of dihydropyridines CCBs End in -Dipine 1st gen (NNN) 2nd gen (FINc) 3rd gen (amlodipine) 3 classes of non-selective CCBs (Non-dihydropyridines) Phenylalkylamines Benzothiazepines Phenylbenzylamine Indications of CCBs (4)...

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CCB Exam 2 Practice Questions and Correct Answers

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Why is cyclin D frequently amplified or over-expressed in human cancers? know that cyclin D is the initiator of the G1 phase of cell cycle and works as the other kinase complexes fluctuates. over expression of cyclin D in turn leads to increased cell division and growth Which part of the cell cycle...

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Pharmacology - Calcium Channel Blockers and Nitrates Questions and Answers

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CCBs mechanism inhibit Ca2+ influx through L-type (voltage gated) calcium channels (LTCC) CCBs actions act on Ca2+ entry into vascular smooth muscle (vasodilate), cardiac muscle (decrease force of contraction), SA nodal tissues (reduce contraction rate), AV node (decrease conduction velocity) Ther...

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Calcium Channel Blockers and Renal Replacement Therapy Questions and Answers

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A 57-year-old woman comes to the physician because of a 2-week history of swelling of both her feet. It improves a little bit with elevation but still is bothersome to her because her shoes no longer fit. She has type 2 diabetes mellitus treated with metformin and linagliptin. She was diagnosed with...

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Calcium Channel Blockers Study Questions and 100% Correct Answers

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CCB absorption nearly complete (low secretion), but most have significant first past effect CCB distribution high protein binding (ex. albumin, glycoproteins); low distribution and high restriction to vascular compartments CCB metabolism CYP3A4 (first pass effect and drug interactions) CCB elimin...

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Calcium Channel Blockers Review Questions and Complete Solutions

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True or False; All Calcium Channel Blockers are racemic mixtures? False diltiazem & nifedipine are not ALL the other currently available CCB's are administered as racemic mixtures What are the three chemical structure classification? Phenylalkylamines, Benzothiazepines, 1,4-Dihydropyridines What...

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Pharm Calcium Channel Blockers & Beta Blockers Study Guide

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What are the L-type Calcium Channel Blockers (CCB)? Non-DHP, oral DHP, IV DHP. Non-DHP: - Verapamil - Diltiazem oral DHP: - Nifedipine - Amlodipine IV DHP: - Nicardipine - CLevidipine CCB Pharmacokinetics (bioavailability, metabolism, half life) Bioavailability: - good oral absorption but reduced...

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Pharm Chapter 45 - Calcium Channel Blockers Study Questions and Correct Answers

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Prototype for calcium channel blocker that affect the heart and blood vessels Verapamil Prototype for calcium channel blocker that is a dihydropyridines: Agents that act mainly on blood vessels Nifedipine Safety Alert: Immediate-release nifedipine has been associated with increased mortality in pa...

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Chapter 45 Calcium Channel Blockers (Study Guide) Q&A

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Complete the phrase: Calcium channel blockers (CCBs) lower blood pressure by ________________: vasodilation Complete the phrase: CCBs differ from nitrates in that they do not cause vasodilation of _______________: veins (venous system) Complete the phrase: Dihydropyridine CCBs primarily affect ___...

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