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Resumen completo sobre BACILOS G + NO ESPORULADOS- BACTERIOLOGÍA.
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Resumen completo sobre BACILOS G + NO ESPORULADOS- BACTERIOLOGÍA. Patologías- diagnóstico, etc.
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FACULTAD DE CIENCIAS MÉDICAS.C ÁT E D R A D E B A C T E R I O L O G Í A
Corynebacterium diphtheriae: difteria.
Mycobacterium tuberculosis Mycobacterium leprae
Práctica : Bacilo Diftérico Tinción de Albert, Bacilo de Koch.
, CORINEBACTERIAS
Corynebacterium diphtheriae 1
Pequeños, finos, pleomorfos
Bacilos Grampositivos, rectos o ligeramente curveados
Diámetro de 0.5 a 1 μm y varios micrómetros de longitud
No móviles, no encapsuladas, no esporuladas
Aerobios
❑ Saprófitas: C. pseudodiphteriticum (difteroides) Biotipos
Gravis
❑ Patógenas: Corynebacterium diphtheriae y Corynebacterium ulcerans Mitis
(toxigénica) Intermedius
, Toxina diftérica 2
Dispersa en sangre
Exotoxina: principal Se produce en el lugar
causa signos
factor de virulencia de la infección
sistémicos
Mediante un Se introduce en las El gen tox que codifica
bacteriófago cepas de C. la exotoxina
lisogénico diphtheriae
Escisión proteolítica de la secuencia adelantada de la proteína tox durante la
secreción desde la pared bacteriana
Escisión de la molécula de la toxina en dos polipéptidos (A y B)
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