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Anti-anginal drugs
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ANTI-ANGINAL DRUGSANGINA PECTORIS:
Typical angina pectoris is a characteristic sudden,
severe, crushing chest pain that may radiate to the neck, Jaw,
back and arms.
Types:
1)Stable angina, effort-induced angina,classic or typical angina:
Classic angina pectoris is the most common form of
angina.It is caused by Coronary occlusion because of atheroma
also known as effort-induced angina.It is usually characterized
by a short lasting burning, heavy or squeezing feeling in the
chest.When the pattern of chest pain and the amount of effort
needed to trigger the chest pain does not vary over time, that
angina is named as “stable angina”.
2)Unstable angina:
It is caused by diminished Coronary flow. Unstable
angina is chest pain that occurs with increased frequency,
duration, and intensity can be precipitated by progressively less
effort. Unstable angina is a form of acute coronary syndrome
and requires hospital admission and more aggressive therapy
to prevent progression to myocardial infarction and death.
3)Prinzmetal,variant,vasospastic,or rest angina:
It involves reversible spasm of coronaries, make a
good addressed or during exercise Prinzmetal angina generally
, responds promptly to coronary dilators, such as nitroglycerin
and calcium channel blockers.
CLASSIFICATION OF ANTI-ANGINAL
DRUGS
1)Nitrites and nitrates:
● Amyl nitrites (extremely volatile liquid)
● Nitroglycerin (moderately volatile liquid)
● Isosorbide dinitrate (solid,sub lingually)
● Isosorbide mononitrate (orally used)
2)Beta adrenergic blockers:
● Atenolol
● Metaprolol
● Propranolol
3)Calcium channel blockers:
● Diltiazem
● Verapamil
● Nifedipine
4)Sodium channel blockers:
● Ranolazine
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