A concise, graphic summary of drugs that affect the CNS including: Sedative hypnotics, Anxiolytics, Anti-depressants, Anti-psychotics, Psychomimetics, Anti-Epileptics, Anti-Convulsants and Anti-Emetics.
CNS drugs
• CNS drugs work on receptors in the brain and spinal chord.
• CNS Neurotransmitters & Receptors
Receptors found in the CNS
Neurotransmitter Receptor Effects
SHT Dopamine
Acetycholine Muscarinic (M1) Excites CNS
Noradrenaline/ A & B adrenergic Weak stimulant
Adrenaline effect
Dopamine Dopaminergic (D1, Excites
D2)
Serotonin (SHT) Serotonergic Excites
GABA (Gamma- GABA (A & B) Depresses
aminobutyric acid)
Opiod peptides Opiod Receptors Depresses
GABA
Levels of CNS
Excitability
Seizures Excess Energy
Anxiety
Excitation
Activation
Homeostasis
Relaxation
Sedation
Sleep
Anesthesia
Coma No Energy
,Sedative Hypnotics
, Anxiety vs Depression
Depression:SLICED Anxiety: HYPERTense
Sadness Hyperventilation
Lack of enjoyment Perspiration, Phobia’s
Insomnia or sleepiness Euphoria
Changes in appetite Restless
Energy decreases Tachycardia, Tremors
Down thoughts (suicidal, despair)
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