Class notes
Aantekeningen college imm1 - introduction in immunology and innate immunity
- Course
- Institution
Uitgebreide aantekeningen van het hoorcollege immunologie 1.
[Show more]
Seller
Follow
biermanannika
Content preview
IMM 1 Introduction in immunology and innate immunityPart 1
Why do we have an immune system?
1. Ensures we stay healthy
2. Protects the body from pathogens and other foreign substances
3. Destroys infected and malignant cells
4. Removes cellular debris
-> How does it do that? The three R’s:
1. Recognize
2. Remove
3. Remember
Our immune system needs to discriminate between self and non self and harmless and harmful.
Self or non-self? Harmless of harmful? Response?
Self Harmless No
Self Harmful Yes
Non-self Harmless No
Non-self Harmful Yes
A disbalance (wrong response) can cause disease:
Self or non-self? Harmless or harmful? Response? Result
Self Harmless Yes Auto-immune disease
Self Harmful No Cancer
Non-self Harmless Yes Allergy
Non-self Harmful No Infection
Cytokine = signalling molecule for activation
Chemokine = signalling molecule for migration
The innate immune system forms the 2nd line of defence (aspecific):
1. Rapid response within hours
2. Fixed
3. Limited number of specificities
4. Constant during the course of response
The adaptive immune system forms the 3rd line of defence (specific):
The benefits of buying summaries with Stuvia:
Guaranteed quality through customer reviews
Stuvia customers have reviewed more than 700,000 summaries. This how you know that you are buying the best documents.
Quick and easy check-out
You can quickly pay through credit card or Stuvia-credit for the summaries. There is no membership needed.
Focus on what matters
Your fellow students write the study notes themselves, which is why the documents are always reliable and up-to-date. This ensures you quickly get to the core!
Frequently asked questions
What do I get when I buy this document?
You get a PDF, available immediately after your purchase. The purchased document is accessible anytime, anywhere and indefinitely through your profile.
Satisfaction guarantee: how does it work?
Our satisfaction guarantee ensures that you always find a study document that suits you well. You fill out a form, and our customer service team takes care of the rest.
Who am I buying these notes from?
Stuvia is a marketplace, so you are not buying this document from us, but from seller biermanannika. Stuvia facilitates payment to the seller.
Will I be stuck with a subscription?
No, you only buy these notes for $3.25. You're not tied to anything after your purchase.
Can Stuvia be trusted?
4.6 stars on Google & Trustpilot (+1000 reviews)
79223 documents were sold in the last 30 days
Founded in 2010, the go-to place to buy study notes for 14 years now