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BIO 669 Assignment 2 Endocrine and Cardiovascular Systems
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BIO 669 Assignment 2 Endocrine and Cardiovascular SystemsBIO 669 Assignment 2 Endocrine and Cardiovascular Systems
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Assignment 2 Endocrine and Cardiovascular Systems1. What effects would these two changes (increased responsiveness to aldosterone and
ADH) have on Na+, K+ and water levels in the plasma? (Endocrine Mod 3: MO2, MO3,
CO2, CO3, CO4)
Increased responsiveness to aldosterone would increase renal reabsorption of sodium and wast-
ing of potassium as hydrogen. The increased retention of sodium would lead to increased reten-
tion of water due to the fact that, in the body, water tends to follow sodium. Increased effective-
ness of ADH decreases the amount of water released by the kidneys as urine, which would also
increase plasma fluid volume (Huether & McCance, 2017).
2. Where does cortisol secretion occur, and thus is a potential site of an over-secreting tu-
mor? How else could someone develop Cushing syndrome if not by a tumor in that area?
(Endocrine Mod 3: MO1, MO2, MO3, CO1, CO2, CO3, CO4, CO5)
Cortisol is secreted from the adrenal glands. A tumor of the adrenal glands, which secretes too
much cortisol, is one potential cause of of Cushing’s syndrome. Another potential cause is long-
term administration of glucocorticoid medications. A pituitary tumor could cause Cushing’s dis-
ease by secreting too much adrenocorticotropic hormone (ACTH), which would lead to hyper-
secretion of cortisol (Huether & McCance, 2017).
3. Which of the following influences the secretion of ACTH? (Endocrine Mod 3: MO1,
MO2, CO1, CO2, CO3)
d) All of the above
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