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NURS 5315 / NURS5315 Sickle Cell Anemia Case Study GRADED A+
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Running head: CASE STUDY 1Sickle Cell Anemia Case Study
Tammi Lesczynski
University of Texas at Arlington College of Nursing and Health Innovation
In partial fulfillment of the requirements of
N5315 Advanced Pathophysiology
John D. Gonzalez DNP, RN, ACNP-BC, ANP-C
March 5, 2019
This study source was downloaded by 100000827506713 from CourseHero.com on 02-08-2022 03:31:45 GMT -06:00
https://www.coursehero.com/file/39041612/Sickle-Cell-Case-Studydocx/
, CASE STUDY 2
Sickle Cell Anemia Case Study
1. The clinical disorder is most consistent with which acid base disorder?
Metabolic acidosis
2. What data in the scenario supports your diagnosis?
CO2 level of 18 mEq/L (mmol/L)
Profuse diarrhea
Respirations 24
3. What caused this person’s acid base imbalance?
Profuse diarrhea
4. Describe the key pathophysiologic concepts.
A. How does this acid base imbalance cause the potassium imbalance noted in this
patient’s labs?
In metabolic acidosis the pH balance becomes more acidic causing the buffer
systems to compensate for excess acid. Bicarbonate helps to increase the pH level which
in turn will help the arterial pH move towards normal range. When this happens hydrogen
ions move into the intracellular space which then causes potassium to move into the
extracellular space. Potassium is then reabsorbed at the apical membrane of the renal
collecting tubule (Huether, 2019). This is what caused the elevated potassium levels in
Ms. X’s lab values.
B. How does the body compensate for the acid base disorder which this patient is
experiencing?
The body will compensate through the respiratory system. When pH is
decreased peripheral chemoreceptors are stimulated in the carotid bodies. This causes
hyperventilation which produces decreased Pco2. The patient’s respiratory rate is 24
which indicates she is attempting to compensate. By hyperventilating she will have a
decrease in Pco2 which will lead to a more normalized bicarbonate/carbon dioxide
ratio and an increase in pH (Costanzo, 2018).
This study source was downloaded by 100000827506713 from CourseHero.com on 02-08-2022 03:31:45 GMT -06:00
https://www.coursehero.com/file/39041612/Sickle-Cell-Case-Studydocx/
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