NURS 5315 IMMUNE practice test QUESTIONS AND ANSWERS
Hypersensitivity is best defined as a(an):
a. Disturbance in the immunologic tolerance of self-antigens
b. Immunologic reaction of one person to the tissue of another person
c. Altered immunologic response to an antigen that results in disease
d. Undetectable immune response in the presence of antigens - answerANS: C
Hypersensitivity is an altered immunologic response to an antigen that results in disease or damage to
the host. The other options are not accurate definitions of hypersensitivity.
A hypersensitivity reaction that produces an allergic response is called:
a. Hemolytic shock
b. Anaphylaxis
c. Necrotizing vasculitis
d. Systemic erythematosus - answerANS: B
Examples of systemic anaphylaxis are allergic reactions to beestings, peanuts, and fish. The other options
are not accurate examples of hypersensitivity
The common hay fever allergy is expressed through a reaction that is mediated by which class of
immunoglobulins?
a. IgE
, b. IgG
c. IgM
d. T cells - answerANS: A
Type I reactions are mediated by antigen-specific IgE and the products of tissue mast cells (see Figure
9-1). The most common allergies (e.g., pollen allergies) are type I reactions. In addition, most type I
reactions occur against environmental antigens and are therefore allergic. The other options do not
accurately identify the mediation factor related to hay fever.
Which type of antibody is involved in type I hypersensitivity reaction?
a. IgA
b. IgE
c. IgG
d. IgM - answerANS: B
Type I reactions are only mediated by antigen-specific IgE and the products of tissue mast cells
Blood transfusion reactions are an example of:
a. Autoimmunity
b. Alloimmunity
c. Homoimmunity
d. Hypersensitivity - answerANS B
Only Alloimmunity (also termed isoimmunity) occurs when the immune system of one individual
produces an immunologic reaction against tissues of another individual
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