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Samenvatting boek 4 farmacologie geneeskunde
- Course
- Institution
Volledige samenvatting farmacologie 3e bachelor geneeskunde boek 4. Met lesnotities. Met glans geslaagd in eerste zit.
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Deel 4 :Geneesmiddelen ivm het cardiovasculair stelsel
,
,
,1. Diuretica
→
urinevolume î ,
nettoverlies v. solutes / 1-1204
-
alle diuretica behalve , spironolactone bereiken ,
de lvminale transport locaties via de
tvbvlaire vloeistof (filtratie te secretie)
alle diuretica , behalve osmot diuretica door de PT
worden actief gesecreteerd
-
.
,
Netron
ËË;÷÷Ä
in terstitium
::
§ DT
<T
T ami loriae -10
osmotische diuretica
☒
al dos -
terone
✗
spirondactone #
00 urine
Algemene opmerkingen diuretica
'
s innemen
morgens
-
indicaties voor
gn zwangerschapSHT 2 Oedeem
-
-
k Combin met andere farmaca →
k ionen stoornissen
-
bij acute toediening
/ starten onderhoudstherapie →
controle met
ionogram
1 is diuretica thiol id en samen actiever ookal hebben
soms zijn apart weinig effect
-
✗ ze
,
controle vocht
goede ✗ ionen
- •
, 1.1 . Kodzuuranhudrase inhibitoren
1.1.1 .
Werking
interstitivm.tt
Lumen
-§ij
"
Hoi-↓
I
Hzld } JA # 12h03
-
↓ CA CA ↑
(021-1-120 > Wat H2O
CA : Sleutelrol in absorptie van Na HW }
vooral thv lvminale membraan in PT
pH lumen ( d Urine ) ↑
CA -
I : ⊖ CA →
minder HCOJ Van lumen naar uiterst itivm - ☐
minder Hro nr interstitivm
↳
pH systemisch
&
Syst acidose bij langdurig gebruik
.
efficiëntie neemt na enkele dagen duidelijk af
1.1.2 .
Product :
Delete201 amide
1. 1.3 .
Farma Colline tien
per oraal
-
-
effect na 30m , Max Nadu ,
werkt 124
dosis bij
aanpassing
-
NF
1.1.4 . Klinisch
gebruik
-
sulfonamide derivaten
open hoeve glaucoom productie ↓
oogvocht
-
:
-
alualinisatie vd urine
diuretica
metabole
alualosetgv gebruik voor HF
-
-
Mountain sicnness : ↓
productie te
pH ↓ Vh ( SF
1.1.5 .
Toxiciteit
-
bijwerkingen tgv alualinisatie Urine ✗ metabole acidose
-
verergeren met / resp . acidose
-
nierstenen
-
hypokt
↓
-
meer ammoniak in systeem circ .
→
encefalopathie
↳ C1 : lever pathol .
hoge dosissen
slaperigheid in
pares the sieën
-
:
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