Summary List of most drugs relevant in medical studies
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Course
Pharmacology
Institution
Jagillonian University School Of Medicine
Book
Pharmacology
My summary of most drugs in the pharmacology course
Includes a long list of the drugs in different categories, with description of their uses, mechanism of action, and positive/negative effects (made as simple as possible)
Easy to locate drugs
Based on medical curriculum
Test Bank For Lippincott Illustrated Reviews: Pharmacology 8th Edition by Karen Whalen||ISBN NO:10,1975170555||ISBN NO:13,978-1975170554||Chapter 1-48||Complete Guide A+.
Antidepressants
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Pharmacology
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1st pharma test
Atracurium MOA - Competitive
antagonist at neuromuscular
junction
Timolol MOA – non selective β blocker
Open angle glaucoma (↓
intraocular pressure)
Long acting?
Pilocarpine Angle closure glaucoma (↓
intraocular pressure)
Dry mouth
Echothiophate MOA – irreversible AChe
inhibitor
Chronic open angle glaucoma (↓
intraocular pressure)
Pralidoxime Treat organophosphate
intoxication (insecticide)
Atracurium MOA – nondepolarizing block
of NMJ, competes with
acetylcholine
Pancuronium MOA – nondepolarizing block
of NMJ, competes with
acetylcholine
Tubocurarine MOA – nondepolarizing block
of NMJ, competes with
acetylcholine
Suxamethonium MOA – depolarizing block of
NMJ, block acetylcholine
action on muscles, ACh
agonist
Succinylcholine MOA – depolarizing block of
NMJ, block acetylcholine
action on muscles, ACh
agonist
Pyridostigmine Myasthenia gravis
Edrophonium MOA – AChE inhibitor
Dianose myasthenia gravis
(MG)
Short acting
2nd pharma test
Sedative-Hypnotic and Anxiolytic Drugs
Reduction of anxiety
Sedative/hypnotic
Anterograde amnesia
Anticonvulsant
Muscle relaxant
MOA - Increase frequency of opening of chloride ion channels coupled to GABA A receptors
Therapeutic uses
Anxiety disorders
Sleep disorders
They cause short-term amnesia
Seizures
Muscular disorders
Adverse effects
Drowsiness
Confusion
Ataxia (at high doses)
Cognitive impairment (amnesia and knowledge retention)
Dependence and withdrawal symptoms
Agitation
Insomnia
Restlessness
Anxiety
Tension
Contraindications
Liver disease and acute angle glaucoma
Alcohol and CNS depressants (enhance effects of hypnotics)
Drugs
Benzodiazepines Therapeutic use Adverse effects Adm/duration
,Alprazolam Short & long-term treatment for panic Mainly: poor/decreased Intermediate (10-
disorders (most effective drug) concentration, drowsiness, & 20h)
fatigue, (rare dizziness,
headache,); withdrawal reactions
in 30% of pts
Chlordiazepoxide Acute treatment of alcohol withdrawal Long (1-3 days)
and related seizures
Clonazepam Chronic anxiety treatment; adjunctive Long acc. to
drug for seizures Lippincott (6-12h)
Most effective drug w. alprazolam
Diazepam MOA – binds & facilitates inhibitory Long (1-3 days);
actions of GABA (can be used in
Chronic anxiety treatment; seizure and conj. w.
acute alcohol withdrawal; muscular anesthetics)
spasms (cerebral palsy, multiple
sclerosis)
Lorazepam Chronic anxiety treatment; seizures and Intermediate (10-
acute alcohol withdrawal 20h); (can be used
[Note: safe in pts w. hepatic impairment] in conj. w.
anesthetics)
Midazolam Premedication for anxiety-provoking Short (1-6h); (can
procedures – causes amnesia and be used in conj. w.
sedation anesthetics)
Triazolam Insomnia (pts who cannot fall asleep) Tolerance after few days; severe Short (3-8h)
withdrawal rebound insomnia;
daytime anxiety, amnesia,
confusion
Flumazenil Reverses effects of benzodiasepines Mainly dizziness, nausea, Only IV, rapid
(antagonist) vomiting, agitation; withdrawal; onset, short
seizure if mixed with TCAs or duration
antipsychotics
Flurazepam Sleep disorders (rarely used) Excessive daytime sedation & Long acting (1-3
accumulation in body days)
(particularly in elderly); mild
withdrawal due to less potency &
slow elimination
Barbiturates
Amobarbital
Pentobarbital (also drug of abuse)
Phenobarbital (Luminal)
Thiopental (Pentothal)
Actions
Depression of CNS – sedation, hypnosis, anesthesia, coma, death
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