Samenvatting Immunologie: overzicht merkers een cytokines
24 views 9 purchases
Course
Immunologie (1048FBDBMW)
Institution
Universiteit Antwerpen (UA)
Geen samenvatting van het hele vak immunologie, wel een overzicht van alle belangrijkste cytokines en merkers die door verschillende cellen geproduceerd worden en/of tot expressie worden gebracht.
Score: 17/20
Bronnen:
Samenvatting gemaakt a.d.h.v. de lessen en PowerPoint’s van Prof. Dr. Didier Ebo & a.d.h.v. Rijkers,
G.T. & Kroese, F.G.M. (2016). Immunologie. Houten: Bohn Stafleu van Loghum
, Cytokines
Macrofagen
Molecule/cytokine Geproduceerd door Doelwit Effect Andere zaken
IFN-γ NK en Th1 en CTL MF Activatie
IFN-γ NK en Th1 MF Antiviraal
IL 12 MF NK Feedback
IL 1 en 6 MF Hersenen Anorexie, koorts,
slaperigheid…
IL 6 MF Lever Synthese acutefase-
eiwitten
IL1, 6 en TNF-α MF Beenmerg Vrijzetting +
activatie neutro’s &
MF (leukocytose,
thrombocytose en
anemie)
IL 1 en TNF-α MF DC Maturatie DC
IL 8 en IL 17 MF (IL 8) Neutro’s Neutro’s aantrekken
Th17 (IL 17)
TNF-α en IL 1, 6 MF Endotheel Endotheel activeren Gevolg:
vasodilatatie en
adhesiemoleculen
IFN-α en -β MF ≠ Antiviraal
Polymorfonucleaire granulocyten
Molecule/cytokine Geproduceerd door Doelwit Effect Andere zaken
IL 5 / Eosinofielen Positief effect IL 5 blokkeren via
mepolizumab
IL 8 en IL 17 MF (IL 8) Neutro’s Neutro’s aantrekken
Th17 (IL 17)
Complement (C5a) / Neutro’s Acitvatie
en IFN-γ
PAMPS/DAMPS, / MC & baso’s Activatie
complement,…
IgE
ILC’s
Molecule/cytokine Geproduceerd door Doelwit Effect Andere zaken
IFN-γ ILC1 / Tegen IC bacteriën
IL 4, 5, 9 en 13 ILC2 / Parasieten &
wondgenezing
IL 17 en 22, TNF ILC3 / IC bacteriën &
wondgenezing
The benefits of buying summaries with Stuvia:
Guaranteed quality through customer reviews
Stuvia customers have reviewed more than 700,000 summaries. This how you know that you are buying the best documents.
Quick and easy check-out
You can quickly pay through credit card or Stuvia-credit for the summaries. There is no membership needed.
Focus on what matters
Your fellow students write the study notes themselves, which is why the documents are always reliable and up-to-date. This ensures you quickly get to the core!
Frequently asked questions
What do I get when I buy this document?
You get a PDF, available immediately after your purchase. The purchased document is accessible anytime, anywhere and indefinitely through your profile.
Satisfaction guarantee: how does it work?
Our satisfaction guarantee ensures that you always find a study document that suits you well. You fill out a form, and our customer service team takes care of the rest.
Who am I buying these notes from?
Stuvia is a marketplace, so you are not buying this document from us, but from seller biomed2017. Stuvia facilitates payment to the seller.
Will I be stuck with a subscription?
No, you only buy these notes for $0.00. You're not tied to anything after your purchase.
