100% satisfaction guarantee Immediately available after payment Both online and in PDF No strings attached
logo-home
Summary MBBS Paediatrics All in One $59.49   Add to cart

Summary

Summary MBBS Paediatrics All in One

 1 view  0 purchase
  • Course
  • Institution

A guide to success in MBBS study! Self-written notes based on lecture notes and Uptodate. The notes cover all materials medical student need to know about paediatrics before they graduate. Detailed coverage on common child diseases (signs and symptoms, investigations, treatment) with convenient t...

[Show more]

Preview 10 out of 882  pages

  • October 18, 2022
  • 882
  • 2022/2023
  • Summary
avatar-seller
TABLE OF CONTENTS

Chapter 1: General Pediatrics

LABORATORY REFERENCE VALUE 6
NORMAL DEVELOPMENT OF CHILD 9
DEVELOPMENTAL MILESTONES 13

Chapter 2: Infective system

HSV INFECTION 17
VZV INFECTION 23
EBV & CMV INFECTION [INFECTIOUS MONONUCLEOSIS (IM)] 31
HHV-6 & 7 INFECTION (ROSEOLA INFANTUM) 37
MUMPS 42
MEASLES 46
RUBELLA 52
HAND-FOOT-MOUTH DISEASE (HFMD) 58
TYPHOID AND PARATYPHOID FEVER 63
RICKETTSIAL DISEASES 68
DENGUE FEVER 73
MALARIA 79


Chapter 3: Respiratory system

FEVER AND RASH 86
COMMON COLD 93
INFLUENZA 100
SINUSITIS (RHINOSINUSITIS) 109
OTITIS MEDIA 115
GAS INFECTION 123
CROUP (LARYNGOTRACHEOBRONCHITIS) 135
ACUTE EPIGLOTTITIS 143
ACUTE BRONCHIOLITIS 148
PNEUMONIA 154
ASTHMA 172




2

,Chapter 4: Cardiovascular system

HEART FAILURE 201
ATRIAL SEPTAL DEFECT (ASD) 230
VENTRICULAR SEPTAL DEFECT (VSD) 238
ATRIO-VENTRICULAR SEPTAL DEFECT (AVSD) 247
PATENT DUCTUS ARTERIOSUS (PDA) 251
COARCTATION OF AORTA 259
TETRALOGY OF FALLOT (TOF) 267
TRANSPOSITION OF GREAT ARTERIES (TGA) 273
CYANOTIC CONGENITAL HEART DISEASES 279
MYOCARDITIS 291
KAWASAKI DISEASE 295
ACUTE RHEUMATIC FEVER/ RHEUMATIC HEART DISEASE 303




Chapter 5: Gastrointestinal system

NEONATAL JAUNDICE
FLUID AND ELECTROLYTES 308
GASTROENTERITIS (GE) 318
MECKEL’S DIVERTICULUM 324
INTUSSUSCEPTION 348
INTESTINAL ATRESIA 352
INTESTINAL MALROTATION 357
HIRSCHSPRUNG DISEASE 363
SHORT GUT SYNDROME 369
GASTROSCHISIS AND OMPHALOCELE 375
WILSON DISEASE 380




Chapter 6: Urological system

URINARY TRACT INFECTION 389
GLOMERULAR DISEASE 402
POST-STREPTOCOCCAL GLOMERULONEPHRITIS (PSGN) 420
NEPHROTIC SYNDROME 426
HEMOLYTIC-UREMIC SYNDROME (HUS) 440
ENURESIS 446




3

,Chapter 7: CNS system

GLOBAL DEVELOPMENT DELAY (GDD) 450
HYPOTONIA AND FLOPPY INFANT 455
CEREBRAL PALSY 457
SEIZURE AND EPILEPSY 469
FEBRILE SEIZURES 487
INFANTILE SPASMS 495
MENINGITIS 500
ENCEPHALITIS 518
BRAIN TUMOURS 521
SPINAL MUSCULAR ATROPHY (SMA) 535
POLIOMYELITIS 540
GUILLAIN-BARRE SYNDROME (GBS) 545

Chapter 8: Hematological System

ANEMIA 550
VITAMIN B12 AND FOLATE DEFICIENCY 564
NEUTROPENIC FEVER 572
THALASSEMIA 576
HEMOPHILIA A & B 591
VON WILLEBRAND DISEASE (VWD) 601
IMMUNE THROMBOCYTOPENIA (ITP) 606
THROMBOTIC THROMBOCYTOPENIC PURPURA (TTP) 615
APLASTIC ANEMIA 620
HEMOPHAGOCYTIC LYMPHOHISTIOCYTOSIS (HLH) 626
LANGERHANS CELLS HISTIOCYTOSIS (LCH) 632
IMMUNODEFICIENCY IN CHILDREN 635

Chapter 9: Endocrine System

PREMATURITY 642
FAILURE TO THRIVE 656
SHORT STATURE 659
PRECOCIOUS PUBERTY 668
DELAYED PUBERTY 680
HYPOPITUITARISM 685




4

,Chapter 10: Rheumatological System

JUVENILE IDIOPATHIC ARTHRITIS 691
HENOCH-SCHOLEIN PURPURA (HSP) 698
JUVENILE DERMATOMYOSITIS 705
SYSTEMIC LUPUS ERYTHEMATOSUS (SLE) 711

Chapter 11: Pediatrics oncology

ACUTE MYELOID LEUKEMIA (AML) 731
ACUTE LYMPHOBLASTIC LEUKEMIA (ALL) 741
LYMPHOMA 751
MYELODYSPLASTIC SYNDROME 770
NEUROBLASTOMA 776
PHAEOCHROMOCYTOMA 783
RHABDOMYOSARCOMA 787
OSTEOSARCOMA 792
HEPATOBLASTOMA 799
WILM’S TUMOUR 802




Chapter 12: Pediatrics syndromes

TUBEROUS SCLEROSIS COMPLEX (TSC) 806
NEUROFIBROMATOSIS (NF) 811
DOWN SYNDROME (TRISOMY 21) 818
PATAU SYNDROME (TRISOMY 13) 835
EDWARDS SYNDROME (TRISOMY 18) 838
KLINEFELTER SYNDROME 841
TURNER SYNDROME 846
NOONAN SYNDROME 852
RUSSELL-SILVER SYNDROME 855
PRADA WILLI SYNDROME 857
BECKWITH-WIEDEMANN SYNDROME 863
MARFAN SYNDROME 868
DIGEORGE SYNDROME 874
WILLIAMS SYNDROME 878
FRAGILE X SYNDROME 880




5

, Laboratory reference value
Complete blood count (CBC)
Red blood cells (RBC)
Haemoglobin (Hb) ♂ 13.5 – 16.5 g/dL
♀ 12.0 – 16.0 g/dL
MCV 80 - 96 fL
MCH 26 – 33 pg
Hematocrit 0.4 – 0.5 L/L
RBC 4.4 – 5.8 x 1012 /L
RDW 11.8 – 15.8 %
Reticulocytes 0.2 – 2.0 %
White blood cells (WBC)
WBC 3.7 – 9.3 x 109 /L
Neutrophils 1.8 – 6.2 x 109 (40 – 80%) /L
9
Lymphocytes 1.0 – 3.2 x 10 (20 – 40%) /L
Monocytes 0.2 – 0.7 x 109 (< 10%) /L
9
Eosinophils 0.0 – 0.5 x 10 (< 5%) /L
9
Basophils 0.0 – 0.2 x 10 (< 1 - 2%) /L
Platelets
Platelet 150 – 450 x 109 /L
*: Values that are bolded are reviewed according to the newest definition in uptodate


Clotting profile
PT 9.3 – 12.1 s
APTT 25.0 – 31.3 s
INR < 1.0
D-dimer < 0.5 mg/L
Fibrinogen 2–4 g/dL


Electrolyte profile
+
Na 136 – 148 mmol/L
K+ 3.6 – 5.0 mmol/L
Cl- 100 - 109 mmol/L
Ca2+ 2.11 – 2.55 mmol/L
PO43- 0.89 – 1.45 mmol/L




6

, Lipid profile
Total cholesterol Desirable < 5.2 mmol/L
Borderline high 5.2 – 6.1 mmol/L
High ≥ 6.2 mmol/L
LDL Optimal < 2.6 mmol/L
Near optimal 2.6 – 3.3 mmol/L
Borderline high 3.4 – 4.0 mmol/L
High 4.1 – 4.8 mmol/L
Very high ≥ 4.9 mmol/L
Triglycerides Normal < 1.7 mmol/L
Borderline high 1.7 – 2.2 mmol/L
High 2.3 – 5.5 mmol/L
Very high ≥ 5.6 mmol/L
HDL Low < 1.0 mmol/L
High ≥ 1.6 mmol/L




Liver function test (LFT)
AST 15 – 38 U/L
ALT 8 – 58 U/L
ALP 42 – 110 U/L
GGT 11 – 62 U/L
Total bilirubin 4 – 23 μmol/L
Conjugated bilirubin <6 μmol/L
Albumin 39 – 50 g/L




Renal function test (RFT)
Urea 3.1 – 7.7 mmol/L
Creatinine 67 - 109 μmol/L
GFR ≥ 90 (90 – 120) mL/min/1.73m2




Thyroid function test (TFT)
TSH 0.35 – 4.80 mIU/L
fT4 12 – 23 mmol/L




7

, Arterial blood gas
pH 7.35 – 7.45
PO2 10.6 – 14.0 kPa
PCO2 4.7 – 6.0 kPa
HCO3- 22 – 26 mmol/L
Base excess -4 - +2 mmol/L




Others
Total protein 68 – 84 g/L
Globulin 24 – 36 g/L
CK 260 – 530 U/L
LDH 118 – 221 U/L
ESR ♂ Age / 2 mm/hr
♀ (Age + 10) / 2 mm/hr




8

, Illustrate textbook of paediatrics: Normal child development
I. Basic paediatrics knowledge
1. Classification of age
 Neonate: < 4 weeks
 Infant: < 1 year
 Toddler: 1 – 2 years
 Young child: 2 – 5 years
 Older child: 6 – 9 years
 Adolescent: 10 – 19 years (WHO)

2. Respiratory rate in children
 Tachypnea in different age groups
• Age < 2 months: > 60 breaths/min
• Age 2 – 12 months: > 50 breaths/min
• Age 1 – 5 years: > 40 breaths/min
• Age ≥ 5 years: > 20 breaths/ min

Age Normal Tachypnea
Neonates < 4 weeks 30 – 50/ min > 60/ min
Infants < 1 year 20 – 30/min > 50/ min
Young child 2 – 5 years 20 – 30/min > 40/ min
Older child 6 – 9 years 15 – 20/min > 30/ min

Age Normal (PEWS)
Infants 1 – 12 months 30 – 50/ min
Toddlers 1 – 3 years old 20 – 40/ min
Pre-school 4 – 6 years old 17 – 33/ min
School age 7 – 12 years old 15 – 30/ min

3. Pulse rate in children
Age Normal
< 1 year 110 – 160/ min
2 – 5 years 95 – 140/min
5 – 12 years 80 – 120/min
> 12 years 60 – 100/min


Age Normal (Uptodate)
0 – 6 months 110 – 180/min
6 months - 1 year 110 – 160/ min
1 – 2 years 90 – 150/min
2 – 5 years 80 – 140/min
5 – 12 years 70 – 120/min
> 12 years 60 – 100/min

4. Blood pressure in children

Age Upper limit of normal of systolic BP
< 1 year 110 mmHg
2 – 5 years 120 mmHg



9

,II. Developmental milestones
1. Background




 4 fields of developmental function
• Development milestones refers to acquisition of important developmental skills
• Normal pattern for acquisition of skills are
o Sequentially constant
o Varies in rate between children
 Median age and limit age
• Median age
o A guide to the pattern to expect in normal development
o Refers to the age when half the population acquire the skill
• Limit age
o A guide to the necessity for further assessment and examination
o Refers to the age when a skill should have been acquired
o Calculated as “Mean + 2 SDs”
 Adjustment for preterm infants
• Assessment of development age according to the expected date of delivery
• Correction is no longer required after about 2 years of age when number of weeks early
the child was born no longer a significant proportion of the child’s life


2. Developmental milestones by median age
Age Gross motor Vision and fine Hearing, speech and Social, emotional
motor language and behavioral
7 months Sits without Transfer objects from Turns to voices Puts food into mouth
support one hand to another Polysyllabic babble Fears strangers
1 year Stands Pincer grip 1st meaning word Drinks with a cup
independently Wave bye-bye
15 – 18 Walks Scribble 6 – 10 words Hold spoon and gets
months independently (18 months) food safely to mouth
(12 – 18 months)
2.5 years Runs and jumps Draws 4-word sentence Dry by day
Parallel play




10

, III. Hearing
1. Hearing checklist
Time Description Example
Shortly after birth  Startles and blinks at sudden noise  Slamming of door
By 1 month  Notices sudden prolonged sound  Vacuum cleaner
By 4 months  Smiles to sound of parent’s voices even when it is
out of sight
By 7 months  Turns immediately to voices
By 9 months  Listens attentively to familiar everyday sound
 Searches for quiet sounds out of sight
 Show pleasure in babbling loudly and tunefully
By 12 months  Respond to own name and other familiar words
 Respond when you say “no” or “bye-bye”


2. Hearing screening for newborn infants




 Evoked otoacoustic emission (EOAE)
• Advantages
o Simple and quick to perform
• Disadvantages
o Affected by ambient voice
o Not a test of hearing but a test of cochlear function
o Misses auditory neuropathy since CN VIII and brain are not tested




11

The benefits of buying summaries with Stuvia:

Guaranteed quality through customer reviews

Guaranteed quality through customer reviews

Stuvia customers have reviewed more than 700,000 summaries. This how you know that you are buying the best documents.

Quick and easy check-out

Quick and easy check-out

You can quickly pay through credit card or Stuvia-credit for the summaries. There is no membership needed.

Focus on what matters

Focus on what matters

Your fellow students write the study notes themselves, which is why the documents are always reliable and up-to-date. This ensures you quickly get to the core!

Frequently asked questions

What do I get when I buy this document?

You get a PDF, available immediately after your purchase. The purchased document is accessible anytime, anywhere and indefinitely through your profile.

Satisfaction guarantee: how does it work?

Our satisfaction guarantee ensures that you always find a study document that suits you well. You fill out a form, and our customer service team takes care of the rest.

Who am I buying these notes from?

Stuvia is a marketplace, so you are not buying this document from us, but from seller carlcarl546. Stuvia facilitates payment to the seller.

Will I be stuck with a subscription?

No, you only buy these notes for $59.49. You're not tied to anything after your purchase.

Can Stuvia be trusted?

4.6 stars on Google & Trustpilot (+1000 reviews)

81311 documents were sold in the last 30 days

Founded in 2010, the go-to place to buy study notes for 14 years now

Start selling
$59.49
  • (0)
  Add to cart