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Samenvatting leerpad C gastro-enterologie farmacologie
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gastro-enterologie farmacologie leerpad C (cursus + powerpoint)
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Leerpad C - gastro - enterologiefarmacologie
1. Gastro-intestinaal stelsel
1.1 Maag- en duodenumpathologie
Ulcus pepticum en GERD (gastro‐esophageal reflux
disease)
Doel: verhogen pH maag
o Antacida: enkel bij lichte reflux klachten
▪ Vb. HCO3 (®Rennie)
o H2‐antihistaminica
▪ Vb. Ranitidine (Zantac®)
o Proton pomp inhibitoren (PPIs)
▪ Vb. Omeprazole (®Losec), Lansoprazole (®Dakar),
Pantoprazole (Pantomed®)
Eradicatieschema Helicobacter pylori: quadruple therapy
Tweemaal per dag gedurende 10 dagen: een PPI (esomeprazol 20
mg, lansoprazol 30 mg, omeprazol 20 mg, pantoprazol 40 mg of
rabeprazol 20 mg) vóór de maaltijd
+ amoxicilline 1 g
+ metronidazol 500 mg
+ clarithromycine 500 mg
1.2 Spasmolytica
Doel relaxatie gladde spiercel
Directe werking
o Vb. Alverine (®Spasmine), mebeverine
o Prikkelbaredarmsyndroom
Indirecte werking: anticholinergica
o Vb. ®Buscopan
o Koliekpijnen
o Anticholinerge nevenwerkingen: droge mond,
visusstoornissen, constipatie, …
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