100% satisfaction guarantee Immediately available after payment Both online and in PDF No strings attached
logo-home
Sumario FAMILIA REOVIRUS $5.89   Add to cart

Summary

Sumario FAMILIA REOVIRUS

 2 views  0 purchase
  • Course
  • Institution

Resumen de las caracteristicas mas importantes de la familia reovirus

Preview 1 out of 4  pages

  • November 13, 2022
  • 4
  • 2022/2023
  • Summary
avatar-seller
REOVIRUS
R: RESPIRATORIO E: ENTERICO O: HUERFANO
• Virus ARN de vertebrados que pueden afectar al sistema gastrointestinal (como los Rotavirus) y a las vías
respiratorias del huésped.
• cápside simetría icosaédrica
• ARN bicatenarios
• Replicación citoplasma
• Envoltura: No
• 60-80 nanómetros de diámetro

SUBFAMILIAS:
1) Sedoreovirinae: son mas laxos, redondeados, sin espículas.
- Genero ROTAVIRUS: virus rotavirus A-G
- Genero ORBIVIRUS: lengua azul, encefalitis equina, peste equina africana, etc.

2) Spinareovirinae: porque tiene espinas
- Genero: ORTHOREOVIRUS: de aves, de mamíferos
- COLTIVIRUS: fiebre del colorado por garrapatas

Propiedades REOVIRUS
- Virión de 60-80 nm.
- Cápside icosaédrica triple (3 capas)
- ARN bicatenario, lineal SEGMENTADO de 10 a 12 segmentos
- Desnudo
- Replicación en citoplasma
- Resistencia: condiciones ambientales y gastrointestinales (temperaturas hasta 50°C, ph: 3-9 y detergentes).
- Inactivación: etanol al 95%, fenol y cloro

ESTRUCTURA
Morfología icosaédrica con cápside TRIPLE capa:
- Capa externa: proteína VP7 (estructural) y VP4
(forma espiculas)
- Capa intermedia: proteína VP6
- Capa interna: ácido nucleico + VP1/VP3+VP2
VP1/VP3 asociado a VP2 son la maquinaria de
replicación del virus

REPLICACION

Las capas externas del retrovirus son atacadas por el
sistema gastrointestinal.
Virus ingresa, se forma endosoma. Dentro del endosoma
pierde la capa externa y gran parte de la intermedia.
El core o nucleocápside sale del endosoma y comienza la
sintesis de ARNm tempranos. Estos mensajeros salen por
canales de proteinas VP6 (de la capa intermedia).
Estos ARNm son tomados por los ribosomas de la celula
eucariota y se producen proteinas estructurales y otras
que suspenden a la celula inhibiendo alguna via
metabólica.

Hay replicación del genoma en el citoplasma formando los
cuerpos de inclusión (efecto citopatico). Se forma la doble cadena ARN. Se produce una continua y grande
replicación viral y ensamblado viral. Llega a haber muchos cuerpos y llenos.

The benefits of buying summaries with Stuvia:

Guaranteed quality through customer reviews

Guaranteed quality through customer reviews

Stuvia customers have reviewed more than 700,000 summaries. This how you know that you are buying the best documents.

Quick and easy check-out

Quick and easy check-out

You can quickly pay through credit card or Stuvia-credit for the summaries. There is no membership needed.

Focus on what matters

Focus on what matters

Your fellow students write the study notes themselves, which is why the documents are always reliable and up-to-date. This ensures you quickly get to the core!

Frequently asked questions

What do I get when I buy this document?

You get a PDF, available immediately after your purchase. The purchased document is accessible anytime, anywhere and indefinitely through your profile.

Satisfaction guarantee: how does it work?

Our satisfaction guarantee ensures that you always find a study document that suits you well. You fill out a form, and our customer service team takes care of the rest.

Who am I buying these notes from?

Stuvia is a marketplace, so you are not buying this document from us, but from seller ceciliaandrade. Stuvia facilitates payment to the seller.

Will I be stuck with a subscription?

No, you only buy these notes for $5.89. You're not tied to anything after your purchase.

Can Stuvia be trusted?

4.6 stars on Google & Trustpilot (+1000 reviews)

78252 documents were sold in the last 30 days

Founded in 2010, the go-to place to buy study notes for 14 years now

Start selling
$5.89
  • (0)
  Add to cart