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NURS 6630 WK 1 Discussion
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Agonist-to-Antagonist The spectrum of Action of Psychopharmacologic Agents A deep understanding of psychopharmacology and the effects of pharmacologic agents used on the patient is critical for advanced for advanced psychiatric mental health nurse practitioner (PMNHP). Ozver et al. (2013) explai...

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  • December 7, 2022
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  • 2022/2023
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NURS 6630 WK 1 Discussion
Agonist-to-Antagonist The spectrum of Action of Psychopharmacologic Agents
A deep understanding of psychopharmacology and the effects of pharmacologic
agents used on the patient is critical for advanced for advanced psychiatric mental health
nurse practitioner (PMNHP). Ozver et al. (2013) explains that medication injuries caused by
providers are more significant than malpractice twenty times in New York a study that can be
used to mirror the importance of understanding what it takes to address mental health issues
pharmacologically successfully. There is further discussion on psychiatric health providers
could include an understanding of what agonist-to-antagonist action refers to when
addressing the pharmacologic agents. Stahl (2013) elaborates more on psychopharmacology
yet simplifies the process as a way of chemical neurotransmission which is more
straightforward terms affects the person’s moods, thoughts, and other brain activities and
depending on the brain outcome there is a need to understand what drug to use to address
the presenting symptoms.
The agonist-to-antagonist spectrum of action of the psychopharmacologic agent can be
thus said to be psychopharmacologic the approach which either potentiates or demise the action
of natural neurotransmitter thus the antagonist which mimics the natural neurotransmitter
competes for the binding site. For example, when the receptor cell is bound to a given agonist
neurotransmitter it will cause the activity attached to the agonist and the opposite is exact that
antagonist blocks the same site to prevent action potential and both can be manipulated with
drugs that mimic and attach to receptor sites.
G couple proteins and Ion gated Channels
G coupled proteins are known to have the most abundant membrane receptors and the g
coupled protein receptors are significant receptors for the majority of drugs including
psychotropic medications and is well known as the only in eukaryotes and of interest due to
abilities in signaling proteins (Zaichao et al., 2014). The g protein has the most abundant
membrane receptors, and the g protein receptors in humans are responsible for specific
functions, each thus making them an excellent attraction for drug binding and interaction. On
the other hand, ion channels are grouped into categories, leakage, and gated channels, and
gated open when binding happens from a chemical or neurotransmitter. For example, biding
cites for gabapentioids involved in calcium and sodium pain modulation can be used (Stevens
& Stephens, 2018).
Epigenetics
Epigenetic can be understood in order of DNA interacting with molecules, activating or

deactivating genes without changing the structure of DNA, or can further, be seen as an

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