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Molecular basis of inheritance Question and Answers
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Molecular basis of inheritance Question and Answers
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Molecular basis of inheritancePart – a ( The DNA )
1) It is established that Deoxyribonucleic Acid( DNA) is the genetic material
for:
1.All living organisms 2. Higher animals
3.At least for majority of living organisms
4. In all forms of life except monerans
2) It is found that Ribonucleic acid(RNA) acts as genetic material in;
1.All viruses 2. Some viruses 3. All bacteria 4. all Protists
3) Study the following and identify the wrong statement about RNA:
1. Mostly functions as mRNA
2. Functions as an adapter and structural molecule
3. Functions as a catalytic molecule in many cases
4. Functions as a catalytic molecule in some cases
4) Which of the following is considered as the most interesting molecule and
also the most abundant genetic material in the living system?
1. DNA 2. RNA 3. Both 1 & 2 4. Nucleoproteins
5) The length of DNA is usually defined as :
1. number of Nucleosides 2. Number of pentose sugars
3.number of nucleotides (or a pair of nucleotide referred to as base pairs)
present in it.
4. Number of phosphates
6) Identify the incorrectly matched pair:
Organism Length of DNA
(1) Bacteriophage ϕ 174 5386 base pairs
(2) Bacteriophage Lambda 48502 base pairs
(3) Eschrechia coli 4×106 base pairs
,(4) Human beings( haploid content ) 3.3 × 109 bp.
(Actually Escherichia coli has 4.6 x10.6bp)
7)Which of the following is not a feature of the double helix model of DNA ?
(1) The two chains have anti-parallel polarity
(2) A purine always comes opposite to a pyrimidine
(3) The pitch of the DNA is 3.4 nm
(4) The two chains are coiled in a left handed fashion
8) Circular DNA is found in:
(1) Viruses (2) Bacteria, chloroplast and mitochondria
(3) Chloroplast and mitochondria alone (4) Bacteria alone
9) Bacterial nucleoid has:
(1) One single-stranded DNA (2) One double-stranded DNA
(3) Two single-stranded DNA (4) Many double-stranded DNAs
10) A nucleoside is formed by:
1. Pentose sugar & phosphate 2. Pentose sugar & a nitrogenous base
3. Nitrogenous base and phosphate 4. Pentose sugar and 2 nitrogenous bases
11) The number of components in a nucleotide is:
1. 4 2. 3 3. 2 4. 5
12) A nucleotide is formed by :
1. Pentose sugar( Ribose or Deoxyribose)
2. Nitrogenous base( one of either purines or pyrimidines)
3. Phosphate group 4. All the above
13) Choose the correct statements with reference to nitrogenous bases:
A. Adenine & guanine are purines
B. Cytosine, thymine and Uracil are pyrimidines
C. Adenine & thymine are purines
D. Guanine & Cytosine are pyrimidines
1. A &B 2. C & D 3. A only 4. B only
.
, 14) Identify the incorrect statement.
1Adenine, guanine and cytosine are common to both DNA &RNA
2 Thymine is present in the nucleotides of DNA only.
3 Uracil is present in RNA in the place of Thymine
4. Adenine & guanine are present in DNA only
15) To form a nucleoside, a nitrogenous base is linked to a pentose sugar:
(1) Through a P-Glycosidic linkage at carbon atom number 1
(2) Through a P-Glycosidic linkage at carbon atom number 5
(3) Through a N-Glycosidic linkage at carbon atom number 1
(4) Through a N-Glycosidic linkage at carbon atom number 5
16) Which of the following is a Nucleotide?
1. Adenosine 2. Guanosine 3. Cytidine & uridine 4. Uridylic acid
17) A nucleotide is formed When a phosphate group is linked to OH of
which carbon atom of a nucleoside through a phosphor-ester linkage?
1. 3’c 2.5’c 3. 1’c 4.2’c
18) A dinucleotide is formed when 2 nucleotides are linked through:
1. 1’-3’ phosphodiester linkage 2. 3’-5’ phosphodiester linkage
3.2’-3’ phosphodiester linkage 4. 3’-4 phosphodiester linkage
19) Match the following and choose the correct option
sno Nitrogenous base Chemical name
A Adenine 1. 2-amino-6-oxypurine
B Guanine ii 6- aminopurine
C Cytosine iii 2,4-dioxy-pyrimidine
D Thymine iv 2-oxy-4-amino pyrimidine
E Uracil V 5-methyl uracil
, 1. A-1,B-ii, C-iii, D-iv & E-V 2. A-ii. B-I, C-IV,D-V & E-iii
3. A-iii,B-iv, C-1, D-ii & E-V 4.A-ii, B-iv, C- I, D-V& E-iii
20) In RNA, every nucleotide residue has an additional OH group present
at-------- ‘C’ position in the Ribose sugar
. 1. 3’ 2. 4’ 3. 2’ 4. 5’
21) Who proposed the term ‘ Nuclein’ for the acidic substance present in
The Nucleus of a cell ?
1. Watson 2. Meischer 3. Altmann 4. Crick
22) In 1953 James Watson and Francis Crick proposed the famous ‘Double
helix’ model for the structure of DNA on the basis of which of the following?
1. X-ray diffraction data produced by Maurice Wilkins & Rosalind Franklin
2. Erwin Chargaff rule ( for a double stranded DNA, the ratios between Adenine &
Thymine and Guanine And Cytosine are constant and equals to one
3. Option 1 only 4. Options Both 1 &2
23) Identify the incorrect feature(s) of Double helix model of DNA :
A. The base pairing confers a very unique property to the polynucleotide chains
B. They are said to be complementary to each other.
C. If The sequence of bases in one strand is known then the sequence in other
strand can be predicted.
D. IF each strand from a DNA (let us call it as a parental DNA) acts as a
template for synthesis of a new strand.
E. The two daughter DNAs thus, produced would not be identical to the
parental DNA molecule.
1. all are correct 2. Except E all are correct
3. Except D &E the rest are correct 4. Except b all others are correct
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