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MOLECULAR BASIS OF INHERITANCE QUESTION AND ANSWERS
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MOLECULAR BASIS OF INHERITANCE QUESTION AND ANSWERS
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MOLECULAR BASIS OF INHERITANCE1. The final proof for DNA as the genetic material (b) Vicia faba
came from the experiments of (c) Drosophila melanogaster
(a) Hershey and Chase (d) E. coli. (NEETII 2016)
(b) Avery, MacLeod and McCarty
8. The equivalent of a structural gene is
(c) Hargobind Khorana
(a) muton (b) cistron
(d) Griffith. (NEET 2017)
(c) operon (d) recon.
2. If there are 999 bases in an RNA that code for a (NEETII 2016)
protein with 333 amino acids, and the base at
position 901 is deleted such that the length of 9. Which of the following rRNAs acts as
the RNA becomes 998 bases, how many structural RNA as well as ribozyme in
codons will be altered? bacteria?
(a) 11 (b) 33 (a) 5S rRNA (b) 18S rRNA
(c) 333 (d) 1 (c) 23S rRNA (d) 5.8S rRNA
(NEET 2017) (NEETII 2016)
3. During DNA replication, Okazaki fragments 10. A molecule that can act as a genetic material
are must fulfill the traits given below, except
used to elongate (a) it should be able to express itself in the
(a) the lagging strand towards replication fork form of ‘Mendelian characters’
(b) the leading strand away from replication fork (b) it should be able to generate its replica
(c) the lagging strand away from the (c) it should be unstable structurally and
replication fork chemically
(d) the leading strand towards replication fork. (d) it should provide the scope for slow
(NEET 2017) changes that are required for evolution.
4. Which of the following RNAs should be most (NEETII 2016)
abundant in animal cell? 11. DNAdependent RNA polymerase catalyses
(a) tRNA (b) mRNA transcription on one strand of the DNA which
(c) miRNA (d) rRNA is called the
(NEET 2017) (a) template strand (b) coding strand
5. Spliceosomes are not found in cells of (c) alpha strand (d) antistrand.
(a) fungi (b) animals (NEETII 2016)
(c) bacteria (d) plants. 12. Which one of the following is the starter codon?
(NEET 2017) (a) UAA (b) UAG
6. The association of histone H1 with a nucleosome (c) AUG (d) UGA
indicates that (NEETI 2016)
(a) DNA replication is occurring 13. Which of the following is required as inducer
(b) the DNA is condensed into a chromatin fibre (s) for the expression of Lac operon?
(c) the DNA double helix is exposed (a) Lactose
(d) transcription is occurring. (NEET 2017) (b) Lactose and Galactose
7. Taylor conducted the experiments to prove semi (c) Glucose
conservative mode of chromosome replication on (d) Galactose
(a) Vinca rosea (NEETI 2016)
, Molecular Basis of Inheritance 341
14. A complex of ribosomes attached to a single The percentages of the other three bases
strand of RNA is known as expected to be present in this DNA are
(a) polypeptide (b) Okazaki fragment (a) G 17%, A 33%, T 33%
(c) polysome (d) polymer. (b) G 8.5%, A 50%, T 24.5%
(NEETI 2016) (c) G 34%, A 24.5%, T 24.5%
(d) G 17%, A 16.5%, T 32.5%.
15. Which one of the following is not applicable
(2015 Cancelled)
to RNA?
(a) Heterocyclic nitrogenous bases 21. Which one of the following is wrongly matched?
(b) Chargaff’s rule (a) Transcription Writing information from
(c) Complementary base pairing DNA to tRNA.
(d) 5’ phosphoryl and 3’ hydroxyl ends (b) Translation Using information in mRNA
(2015) to make protein.
(c) Repressor protein Binds to operator to
16. Balbiani rings are sites of stop enzyme synthesis.
(a) polysaccharide synthesis (d) Operon Structural genes, operator and
(b) RNA and protein synthesis promoter.
(c) lipid synthesis (2014)
(d) nucleotide synthesis. (2015)
22. Transformation was discovered by
17. Identify the correct order of organisation of (a) Meselson and Stahl
genetic material from largest to smallest. (b) Hershey and Chase
(a) Genome, chromosome, gene, nucleotide (c) Griffith
(b) Chromosome, genome, nucleotide, gene (d) Watson and Crick. (2014)
(c) Chromosome, gene, genome, nucleotide
23. Select the correct option.
(d) Genome, chromosome, nucleotide, gene
Direction of Direction of reading of
(2015)
RNA synthesis the template DNA
18. Satellite DNA is important because it strand
(a) does not code for proteins and is same in (a) 5 – 3 3 – 5
all members of the population (b) 3 – 5 5 – 3
(b) codes for enzymes needed for DNA (c) 5 – 3 5 – 3
replication (d) 3 – 5 3 – 5 (2014)
(c) codes for proteins needed in cell cycle
(d) shows high degree of polymorphism in 24. Which of the following statements is not true
population and also the same degree of of two genes that show 50% recombination
polymorphism in an individual, which is frequency?
heritable from parents to children. (a) The gene show independent assortment.
(b) If the genes are present on the same
(2015)
chromosome, they undergo more than one
19. Gene regulation governing lactose operon of crossovers in every meiosis.
E.coli that involves the lac I gene product is (c) The genes may be on different chromosomes.
(a) negative and repressible because repressor (d) The genes are tightly linked.
protein prevents transcription (NEET 2013)
(b) feedback inhibition because excess of
25. The diagram shows an important concept in
galactosidase can switch off transcription
the genetic implication of DNA. Fill in the
(c) positive and inducible because it can be
blanks A to C.
induced by lactose
(d) negative and inducible because repressor DNA A mRNA B Protein Proposed by C
protein prevents transcription.
(2015 Cancelled) (a) A Transcription, B Translation, C
Francis Crick
20. In sea urchin DNA, which is double stranded, (b) A Translation, B Extension, C Rosalind
17% of the bases were shown to be cytosine. Franklin
, 342
Chapterwise NEETAIPMT SOLUTIONS
(c) A Transcription, B Replication, C James
(a) VNTR (b) SSCP
Watson
(c) SCAR (d) AFLP.
(d) A Translation, B Transcription, C Ervin
(Karnataka NEET 2013)
Chargaff (NEET 2013)
26. Which enzyme will be produced in a cell if 33. Removal of introns and joining of exons in a
there is a nonsense mutation in the lac Y gene? defined order during transcription is called
(a) Transacetylase (a) looping (b) inducing
(b) Lactose permease and transacetylase (c) slicing (d) splicing. (2012)
(c) galactosidase 34. If one strand of DNA has the nitrogenous base
(d) Lactose permease (NEET 2013) sequence as ATCTG, what would be the
complementary RNA strand sequence?
DNA C (a) TTAGU (b) UAGAC
27. mRNA B Protein
Proposed by
A
(c) AACTG (d) ATCGU (2012)
The figure gives an important concept in the
35. Ribosomal RNA is actively synthesized in
genetic implication of DNA. Fill the blanks
(a) lysosomes (b) nucleolus
A, B and C.
(c) nucleoplasm (d) ribosomes.
(a) AMaurice Wilkins, BTranscription,
CTranslation (2012)
(b) AJames Watson, BReplication, C 36. Which one of the following is not a part of a
Extension transcription unit in DNA?
(c) AErwin Chargaff, BTranslation, (a) The inducer (b) A terminator
CReplication (c) A promoter (d) The structural gene
(d) AFrancis Crick, BTranslation, (2012)
CTranscription 37. Removal of RNA polymerase III from
(Karnataka NEET 2013) nucleoplasm will affect the synthesis of
28. Satellite RNAs are present in some (a) tRNA (b) hnRNA
(a) viroids (b) prions (c) mRNA (d) rRNA. (2012)
(c) bacteriophages (d) plant viruses.
38. What are the structures called that give an
(Karnataka NEET 2013)
appearance as ‘beadsonstring’ in the
29. Which of the following is not a property of the chromosomes when viewed under electron
genetic code? microscope?
(a) Nonoverlapping (b) Ambiguous (a) Genes (b) Nucleotides
(c) Degeneracy (d) Universal (c) Nucleosomes (d) Base pairs (2011)
(Karnataka NEET 2013)
39. The unequivocal proof of DNA as the genetic
30. Genes of interest can be selected from a
material came from the studies on a
genomic library by using
(a) bacterium (b) fungus
(a) cloning vectors
(c) viroid (d) bacterial virus.
(b) DNA probes
(Main 2011)
(c) gene targets
(d) restriction enzymes. 40. Which one of the following does not follow
(Karnataka NEET 2013) the central dogma of molecular biology?
(a) Pea (b) Mucor
31. In an inducible operon, the genes are
(c) Chlamydomonas (d) HIV (2010)
(a) usually not expressed unless a signal turns
them”on”. 41. Which one of the following palindromic base
(b) usually expressed unless a signal turns sequences in DNA can be easily cut at about
them “off”. the middle by some particular restriction
(c) never expressed enzyme?
(d) always expresser.
(a)
(Karnataka NEET 2013)
32. One of the most frequently used techniques (b)
in DNA fingerprinting is
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