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Samenvatting Morfologie hart & bloedvaten - prof. Verbrugghe (E02Y9A) $3.78   Add to cart

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Samenvatting Morfologie hart & bloedvaten - prof. Verbrugghe (E02Y9A)

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Samenvatting morfologie hoofdstuk 1 van prof. Verbrugghe. Dit is deel van het vak bloedsomloop (E02Y9A). Hoofdstuk 2 & 3 is via kennisclips online en werd hier NIET samengevat.

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  • January 2, 2023
  • 14
  • 2022/2023
  • Summary
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Bloed & bloedsomloop: inleiding
Morfologie van het bloed
Inleiding
- 5-6 liter bloed
- 8% lichaamsgewicht
- 75-80 ml per kg lichaamsgewicht

In bloed:
- Plasma: extracellulair vocht met eiwitten & globulines
- Bloedcellen: RBC, WBC, bloedplaatjes/chromocyten

Indien uitstrijkje nemen: bloeddruppel op glaasje + kleuring
 Verschillende bloedcellen onderscheiden




Samenstelling plasma:
- Water
- Electrolyten
- Eiwitten (7 g/dl)
o Albumine, alpha-globuline, alpha2-globuline, beta-globuline, fibronogeen
o Onderscheiden via elektroforese
- Koolhydraten
- Lipiden


Plasma <-> serum:
Fig 1-1

Plasma = bloedstaal + antistolling
Serum = bloedstaal na klontervorming

Plasma proteïnen & serum proteïnen ongeveer hetzelfde:
- Bandje normaal met fibrogeen is afwezig in serum
- Logisch want stolsel in fibrinogeen omgezet in fibrine
 Daardoor afwezig

, Het beenmerg
= plaats aanmaak bloedcellen

Links: embryonaal stadium
 Bloedcellen gemaakt in dooierzak

Aanmaak bloedcellen:
Foetale leven → milt & lever
Postnatale leven → in rode beenmerg

!! Hoe jonger, hoe meer aanmaak in lange beenderen
MAAR: hoe ouder hoe vetter de lange beenderen
 Aanmaak in axiaal skelet




Fig 1-2

De beenmerg botboor
= naald in sternum (axiaal skelet)
- Donker gekleurde rbc aanwezig

Links: H&E kleuring
Rechts: wrights kleuring

Megakaryocyten aangeduid met pijltjes
 Grote cellen
 Hieruit thrombocyten ontstaan

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