Summary
Summary Silverthorn Chapter 22 - Metabolism and energy balance
- Course
- Institution
Summary Silverthorn Chapter 22
[Show more]
3 reviews
By: sophievandijk10 • 1 year ago
By: stevensavelberg • 1 year ago
By: stevensavelberg • 1 year ago
Seller
Follow
kipsten
Reviews received
Content preview
SILVERTHORNCHAPTER 22 – METABOLISM & ENERGY BALANCE
APPETITE AND SATIETY
The model for behavioural regulation of food intake is based on two hypothalamic centers: feeding
center that is tonically active and a satiety center that stops food intake by inhibiting the feeding
center. There are two theories for regulation of food intake:
1. Glucostatic theory – glucose metabolism by hypothalamic centers regulate food intake.
When blood glucose concentrations decrease, the satiety center is suppressed and the
feeding center is dominant. When glucose metabolism increases, the satiety center inhibits
the feeding center.
2. Lipostatic theory – a signal from the body’s fat stores to the brain modulates eating
behaviour so that the body maintains a particular weight. If fat stores are increased, eating
decreases. In times of starvation, eating increases. Obesity is the result of disruption of this
Leptin acts a negative-feedback signal between adipose tissue and the brain. As fat stores
increase, adipose cells secrete more leptin en food intake decreases. Leptin is synthesized in
adipocytes under control of the obese (ob) gene.
Neuropeptide Y (NPY) is a brain neurotransmitter that seems to be the stimulus for food intake.
Leptin inhibits NPY in negative feedback pathway. Ghrelin is secreted by the stomach during
fasting and increases hunger.
Silverthorn – chapter 22: Metabolism & energy balance Page 1 of 12
The benefits of buying summaries with Stuvia:
Guaranteed quality through customer reviews
Stuvia customers have reviewed more than 700,000 summaries. This how you know that you are buying the best documents.
Quick and easy check-out
You can quickly pay through credit card or Stuvia-credit for the summaries. There is no membership needed.
Focus on what matters
Your fellow students write the study notes themselves, which is why the documents are always reliable and up-to-date. This ensures you quickly get to the core!
Frequently asked questions
What do I get when I buy this document?
You get a PDF, available immediately after your purchase. The purchased document is accessible anytime, anywhere and indefinitely through your profile.
Satisfaction guarantee: how does it work?
Our satisfaction guarantee ensures that you always find a study document that suits you well. You fill out a form, and our customer service team takes care of the rest.
Who am I buying these notes from?
Stuvia is a marketplace, so you are not buying this document from us, but from seller kipsten. Stuvia facilitates payment to the seller.
Will I be stuck with a subscription?
No, you only buy these notes for $6.71. You're not tied to anything after your purchase.
Can Stuvia be trusted?
4.6 stars on Google & Trustpilot (+1000 reviews)
83430 documents were sold in the last 30 days
Founded in 2010, the go-to place to buy study notes for 14 years now