NAPLEX Test Bank Final

Binds to cell membrane causing depolarization, DNA/RNA/protein synthesis inhibition - Answer- Daptomycin Ceftaroline adverse effects (3) - Answer- Positive direct Coombs' test Thrombocytopenia post-marketing caution renal impairment Inhibits bacterial protein synthesis by binding to 50S FDA approved for complicated skin and skin structure infections - Answer- Quinupristin/Dalfopristin 7.5 mg/kg q8hr Quinupristin/Dalfopristin adverse effects (3) - Answer- hyperbilirubinemia pain/INF at infusion sites myalgia Covers aerobic/anaerobic bacilli - Answer- 2G Ceph (Cefuroxime) Concentration-dependent bacteriocidal that covers GM , GN , mycobacterium, and atypicals - Answer- Fluoroquinolones (Ciprofloxacin) Prothrombin Complex Conc (PCC) max dose - Answer- 20 mL/min 6 mg/kg IV daily - Answer- Daptomycin dose Docetaxil side effect - Answer- neutropenia Trad AG (Gent/Tobra) dose - Answer- 1-2.5 mg/kg IV q8hr Peak 5-10, Trough 2 LABA Olodaterol MDI daily - Answer- Striverdi Respimat CYP-450 Inhibitors BIG FACES.COM - Answer- Bupropion, Itraconazole, Gemfibrazole Fluoxetine, Amiodarone, Cipro Erythromycin, SMX-TMP, Clopidogrel Omeprazole, Metronidazole Lefluonamide (Arava) DMARD reversal agent - Answer- Cholestyramine 8 mg TID for 11 days (OUTCH) What antihypertensive class should avoid GFJ? - Answer- All CCB are CYP3A4 substrates Room temp stor