Immunochemistry is the study of the chemistry of the immune system. This involves the study of the properties, functions, interactions and production of the chemical components (antibodies/immunoglobulins, toxin, epitopes of proteins like CD4, antitoxins, cytokines/chemokines, antigens) of the immu...
12.1 Immune System
Ø Multiple layers of protection against invading organisms.
2 Major Parts of Immune System
Innate Immunity Adaptive Immunity
Ø First line of defense against foreign Ø Second line of defense against
invaders. foreign invaders.
4 Types of Innate Immunity Components f Adaptive Immune
1. Phagocytes System
1. Antigens
2. Dendritic Cells 2. Antibodies
3. Macrophages 3. Lymphocytes
4. Natural Killer Cells T cells
B cells
, Immunoglobulin Superfamily
Ø Basic molecules of the immune system.
2 Domains of Immunoglobulin Superfamily
Constant Region
Ø Same amino acid sequence in each molecules.
Variable Region
Ø Unique amino acid sequence in each molecules
3 Dimensional Representation of Immunoglobulin Superfamily
1. Secreted by plasma cells.
2. Receptors on the surface of T cells.
3. Known as Major Histocompatibility Complexes (MHC).
,12. 2 Organs & Cells
that makes up the
Immune System
A. Lymphoid
Organs
B. Cells of the
Internal Innate
Immunity
C. Cells of
Adaptive
Immunity
, A. Lymphoid Organs
LYMPHATIC SYSTEM
• Web of lymphatic vessels containing a clear fluid (lymph) and tissues and
organs located throughout the body.
LYMPHOID ORGANS
• Lymphatic vessels circulate throughout the body.
LYMPHOCYTES
• Specialized white blood cells.
T CELLS
• Originate in the bone marrow
but mature in the thymus gland.
B CELLS
• Originate and mature the bone
marrow.
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