Methicilline Stahpylokokken Penicilline
Niet meer bij patiënten
Gebruikt bij diffusie-antibiogram
Vervangen door Cefoxitine en Oxacilline
Ampiciline Gram positieven Klebsiella resistent
Gram negatieven
Amoxicilline Gram positieven Enterobacter spp. resistent tegen
Gram negatieven
Ticarcilline P. aeruginosa Carboxypenicilines
Piperracilline P. aeruginosa Carboxypenicillines
Amoxiclav remt β-lactamasen Amoxicilline + clavulaanzuur
Temocilline Aërobe G- staafjes +: stabiel tegen ESBL
→ remt geen β-lactamasen -: niet werkzaam tegnen G+, non-
P. aeruginosa fermenteerders en anaerobe
Diverse ziekenhuiskiemen
Cefazoline Streptokokken 1ste generatie Cefalosporines
S.aureus
Enkele gram-negatieven
Cefaclor Streptokokken 2de generatie Cefalosporines
S.aureus
Enkele gram-negatieven
H. influenzae
Cefuroxime Streptokokken 2de generatie Cefalosporines
S.aureus
Enkele gram negatieven
H.influenzae
Cefoxitine Streptokokken 2de generatie Cefalosporines
S.aureus Werking: bindt en inactiveert PBPs
Enkele gram negatieven MRSA stammen resistent
H.influenzae Stabieler tegen beta-lactamase
Ceftazidime
Ziekenhuis enterobacteriaceae 3de generatie Cefalosporines
P.aeruginosa Bij ernstige infecties: stabieler tegen beta-
lactamase
Ceftriaxone
Ziekenhuis enterobacteriaceae 3de generatie Cefalosporines
Bij ernstige infecties doordat stabieler tegen
beta-lactamase
Aztreonam Ziekenhuis enterobacteriaceae Monobactams
Gram negatieven Lage toxiciteit
Gebruik bij ernstige infecties doordat stabieler
tegen beta-lactamase
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