UNE CHEM 1005: MEDICAL BIOCHEMISTRY FINAL EXAM
QUESTIONS WITH COMPLETE SOLUTIONS
Carnitine palmitoyl transferase correct answer: - transfers acyl
groups from CoA to carnitine & vice versa
- inhibited by malonyl-CoA
ketone bodies correct answer: - acetoacetate, β-
hydroxybutyrate, acetone
- oxidized as fuel source in extreme fasting
d-3-hydroxybutyrate dehydrogenase correct answer:
interconversion of acetoacetate and 3-hydroxybutyrate
acetone correct answer: yielded by spontaneous
decarboxylation of acetoacetate; waste product
acetoacetate and 3-hydroxybutyrate correct answer: - ketone
bodies produced during fasting
- used for energy in various tissues
hyperglycemia and ketogenesis correct answer: - occurs in
fasted state
- loss of insulin (type 1 diabetes)
Ketogenesis correct answer: the process by which excess
acteyl-CoA is converted into ketone bodies
products of B-oxidation of fatty acids correct answer: - NADH
- FADH2
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