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Summary bleeding- coagulation cascade
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haematology bleeding for medical students
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Bloodlines of Health: The Vital Role of Hematology
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CMP-clotting (coagulation cascade)
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Department of MedicineCommon Medical Presentation: Bleeding
,Learning Outcomes
• Apply the key components of history taking and examination to patients
presenting with bleeding
• Formulate an appropriate differential diagnosis, and investigations list, w
justification for each
• Interpret the results of history taking, examination and investigations for
purpose of diagnosis
• Discuss appropriate investigations used in diagnosing bleeding issues a
their underlying causes
• Outline the principles of management for patients presenting with bleedi
,Bleeding Disorders
A group of disorders that share the inability to form a proper blood clot.
They are characterized by extended bleeding after injury, surgery, trauma o
menstruation, may also be spontaneous.
They all arise from either a platelet problem or a clotting factor problem.
, Case 1
A 21 year old man presents to the emergency department
complaining of a one day history of a painful swollen right
knee with no antecedent trauma. He reports a similar
presentation last year where the same knee was affected.
A diagnostic joint aspiration reveals a haemarthrosis.
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