Monitoring Parameters for antivirals such as acyclovir(Zovirax)/valacyclovir(Valtrex)? - ANSWER 10% liver/90% kidney = BUN, Creat, LFT
What is the Class and MOA of carbamazepine (tegretal) & topiramate (Topamax)? - ANSWER Anticonvulsant; thought to block Na+ channels to slow activity or ...
What precautions should be taken when discontinuing Carbamazepine? -
ANSWER Do Not stop abruptly; half life drops from 30 hr to 15 over time
What is GABA? - ANSWER calming/inhibitory neurotransmitter; calms firing
nerves in CNS; high levels improve focus, low levels cause anxiety
What is serotonin? - ANSWER mood neurotransmitter; Affects mood, hunger,
sleep, and arousal
What is norepinephrine/noradrenaline? - ANSWER Concentration
neurotransmitter; affects attention and responding actions; fight or flight
What is dopamine? - ANSWER pleasure neurotransmitter; feelings of pleasure,
addiction, motivation
What is acetylcholine? - ANSWER parasympathetic neurotransmitter that
diffuses across a synapse and produces an impulse in the cell membrane of a
muscle cell
, Maryville NURS615 Pharm 2 exam 2023
LATEST QUESTIONS WITH COMPLETE
SOLUTIONS RATED (A+)
What should families be taught regarding the monitoring of seizure activity? -
ANSWER focus on prevention, pt safety, quality of life; if seizure occurs
notefrequency, duration, severity; be aware of mood changes, depression, anxiety,
suicide; establish mutual treatment goals, DO NOT stop meds abruptly
What electrolyte imbalance is noted with Topiramate (Topamax) & what to monitor?
- ANSWER a decrease in serum bicarbonate concentration, leading to
hyperchloremic metabolic acidosis; CMP & bicarb
Adverse effects seen with topiramate (Topamax) and pregnancy risk? - ANSWER
ocular syndromes (myopia and angle
closure glaucoma), ↓sweating (oligohidrosis), hyperthermia; in pregnancy: ↑risk of
cleft lip in infants
What is the MOA for Levetiracetam (Keppra) - ANSWER Does not affect GABA;
may prevent epileptiform burst firing and spread of seizure activity.
What population is Levetiracetam (Keppra) safer for? - ANSWER Children and
pregnancy
What are the pregnancy precautions for valproate (Depakote) - ANSWER Cat X;
known teratogen; if necessary take after 1st trimester
Education for women taking valproate (Depakote) wanting to get pregnant? -
ANSWER possibility of birth defects, switch meds, be followed by high-risk OB
What should be monitored commonly with all anticonvulsants? - ANSWER their
levels
What are the precautions and contraindications for the tricyclic antidepressants
(TCA)? - ANSWER Cardiac conduction disorder causing prolonged QT, get
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