NBME - Behavioral Science:
Epidemiology/Biostatistics/Questions
With Complete Soutions
Quiz :Cross-sectional study (observational) - √Answer :Collects data from a
group of people to assess frequency of disease at a particular point in time.
Asks, "What is happening?"
Quiz :Cross-sectional study (observational) - √Answer :Measures disease
prevalence - can show risk factor association with disease, but does not
establish causality.
Quiz :Case-control study - √Answer :Compares a group of people with disease
to a group without disease. Asks, "What happened?"
Quiz :Case-control study - √Answer :Measures and odds ratio (OR) - "Patients
with COPD had a higher odds of a history of smoking than those without
COPD."
Quiz :Cohort study - √Answer :Compares a group with a given exposure or risk
factor to a group without such exposure. Looks to see if exposure increases risk
for disease.
Quiz :Cohort study - √Answer :Measures relative risk (RR) = 'Smokers had a
higher risk of developing COPD than nonsmokers."
Quiz :Twin concordance study - √Answer :Compares the frequency with which
both monozygotic twins or both dizygotic twins develop the same disease.
Quiz :Twin concordance study - √Answer :Measures heritability and influence
of environmental factors (nature vs. nurture).
Quiz :Clinical trial - √Answer :Experimental study involving humans that
compares therapeutic benefits of 2 or more treatments, or of treatment and
placebo.
Quiz :Phase I clinical trial - √Answer :An experiment with a small number of
healthy volunteers - assesses safety, toxicity, and pharmacokinetics - "Is it
safe?"
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