,Q. 4. Q. : Which of the following attaches skeletal muscle to bone?
Student Answer: Tendon
Ligament
Bursa
Mesentery
Instructor
A tendon is fibrous connective tissue that attaches skeletal muscle to bone.
Explanation:
Points Received: 2 of 2
Comments:
Q. 5. Q. : Which statement is false about giant cell tumors?
They are an overexpression of genes including osteoprotegerin lig&
Student Answer:
(OPGL).
They are malignant, solitary, irregularly shaped tumors.
They are typically located in the epiphysis in the femur, tibia, radius, &
humerus.
They are slow-growing tumors that extend over the articular cartilage.
Instructor The giant cell tumor is generally a benign, solitary, circumscribed tumor that
Explanation: causes extensive bone resorption because of its osteoclastic origin.
Points Received: 2 of 2
Comments:
Considering the pathophysiology of osteoporosis, what are the effects
Q. 6. Q. : of extracellular signal regulated kinases (ERKs) & receptor activator of
RANKL on osteoblasts & osteoclasts?
ERKs increase the life span of osteoclasts & RANKL decreases the
Student Answer:
life span of osteoblasts.
ERKs & RANKL increase the life span of osteoclasts & decrease the
life span of osteoblasts.
ERKs & RANKL increase the life span of osteoblasts & decrease the
life span of osteoclasts.
ERKs increase the life span of osteoblasts & RANKL decreases the
life span of osteoclasts.
In addition to ERKs, RANKL is required for the antiapoptotic & thus longer life
Instructor span of osteoclasts. These effects increase the life span of osteoclasts (i.e.,
Explanation: longer bone resorbing) & shorten the life span of the bone-forming cells, or
osteoblasts.
Points Received: 2 of 2
Comments:
What is the diagnosis of a person who has tennis elbow characterized
Q. 7. Q. :
by tissue degeneration or irritation of the extensor carpi brevis tendon?
Student Answer: Lateral epicondylitis
, Medial tendinitis
Bursitis
Lateral tendinitis
Instructor Lateral epicondylopathy, commonly called tennis elbow, is the result of tissue
Explanation: degeneration or irritation of the extensor carpi radialis brevis tendon at its origin.
Points Received: 2 of 2
Comments:
Q. 8. Q. : Cerebral palsy is usually a result of
Student Answer: brain ischemia during birth.
prematurity.
congenital defects.
genetic defect.
Instructor Cerebral palsy is a static disorder of muscle tone & balance caused by an
Explanation: ischemic insult to the brain, usually perinatally.
Points Received: 2 of 2
Comments:
Molecular analysis has demonstrated that osteosarcoma is associated
Q. 9. Q. :
with
Student
TP53.
Answer:
src.
myc.
TSC2.
Instructor
The oncogene src also has been associated with osteosarcoma.
Explanation:
Points Received: 2 of 2
Comments:
Q. 10. Q. : Ewing sarcoma arises from
Student Answer: bone marrow.
bone-producing mesenchymal cells.
metadiaphysis of long bones.
embryonal osteocytes.
Instructor Arising from bone marrow, Ewing sarcoma can break through the cortex of the
Explanation: bone to form a soft-tissue mass.
Points Received: 2 of 2
Comments:
Q. 11. Q. : Which protein, absent in muscle cells of Duchenne muscular
dystrophy, mediates the anchoring of skeletal muscles fibers to the
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